Paraviral exanthems

Abstract

We covered the clinical manifestations and managements of pityriasis rosea, pityriasis lichenoides, and Gianotti-Crosti syndrome. Expert Commentary: Most patients with pityriasis rosea do not need any active intervention. Symptomatic relief of the pruritus would be adequate. For patients with pityriasis rosea that are serious, extensive, or causing severe impacts of their quality of life, oral acyclovir could be considered. For pityriasis lichenoides, managements would be depending on the type of the exanthem such as the acute form (pityriasis lichenoides et varioliformis acuta, also known as Mucha Habermann disease) the chronic form (pityriasis lichenoides chronic Juliusberg's disease), and the febrile ulceronecrotic Mucha-Habermann disease, which is a complication of the acute form. The management of Gianotti-Crosti syndrome is mainly symptomatic. The need for long-term follow-up for chronic complications of the underlying viral infections is still controversial.

Pityriasis Rosea during Pregnancy: Major and Minor Alarming Signs

“…Antiviral therapies, such as acyclovir or valacyclovir, may be contemplated when the degree of risk for the pregnancy or birth outcome are very high. Acyclovir is effective in HHV-6 infection [19] and gives symptomatic relief in PR [20]. Regrettably, acute renal failure secondary to acyclovir is a well-described side effect, with the most common mechanism being crystal nephropathy, and a case of nephrotoxicity has been reported in a woman at 32 weeks of pregnancy who had been treated for possible chickenpox [21].…”

Multiple “angiomas” in a 14‐month‐old infant

“…First described by Cherry JD et al in 1969 [ 1 ] , eruptive pseudoangiomatosis is considered to be a paraviral exanthem [ 2 ] . The disease is clinically characterized by an acute (eruptive) onset of disseminated angioma-like papules (blanchable on diascopy) on the face and extremities that occur 1-2 weeks after an upper respiratory or gastrointestinal infection [ 3 ] .…”

It looks like childhood eczema but is it?

“…Occasionally, vesicles may be seen. The syndrome is regarded as a self‐limiting cutaneous response to an infection, typically hepatitis virus and EBV …”