Parenchymal-sparing hepatectomies (PSH) for bilobar colorectal liver metastases are associated with a lower morbidity and similar oncological results: A propensity score matching analysis

Méméo, Riccardo; Association, French Surgical

doi:10.1016/j.ejso.2018.01.067

Cited by 4 publications

(4 citation statements)

References 29 publications

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“…Strategies based on PSH were initially described by Gold et al [25], who demonstrated that multiple uni-or bilobar liver resections (wedge resections) respecting the uninvolved liver parenchyma have no negative impact on oncological outcomes if R0 resection is completed. Similar results were subsequently obtained by several authors in terms of diseasefree survival (DFS) and OS with lower rates of general complications (25 vs. 34%; p = 0.03) and type Dindo-Clavien III-IV (10 vs. 16%, p = 0.04) when compared with standard or extent hepatectomies [26].…”

Section: Low-risk Resectable Patientssupporting

confidence: 85%

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

et al. 2019

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Colorectal cancer (CRC) has the second-highest tumor incidence and is a leading cause of death by cancer. Nearly 20% of patients with CRC will have metastases at the time of diagnosis, and more than 50% of patients with CRC develop metastatic disease during the course of their disease. A group of experts from Medicine and Molecular Imaging met to discuss and provide a multidisciplinary consensus on the management of liver metastases in patients with CRC. The group defined the different scenarios in which the disease can present: fit or unfit patients with resectable liver metastases, patients with potential resectable liver metastases, and patients with unresectable liver metastases. Within each scenario, the different strategies and therapeutic approaches are discussed.

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Section: Low-risk Resectable Patientssupporting

confidence: 85%

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

et al. 2019

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“…All data were collected from a multicenter French registry of patients who underwent hepatectomy for colorectal LM at 24 hospitals from 2006 to 2013 as previously described [7][8][9][10][11].…”

Section: Methodsmentioning

confidence: 99%

Primary Tumor Versus Liver‐First Approach for Synchronous Colorectal Liver Metastases: An Association Française de Chirurgie (AFC) Multicenter‐Based Study with Propensity Score Analysis

et al. 2018

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“…La PP (resecciones económicas) han demostrado menor tasa de morbilidad global, menor riesgo de falla hepática aguda y menor necesidad de cuidados intensivos postoperatorios. Además, tienen la ventaja de favorecer las re-resecciones en caso de recurrencia, siendo actualmente el estándar 18,19 .…”

Section: Resecciones Anatómicas (Ra) Vs Preservación De Parénquima (Pp)unclassified

Tratamiento Quirúrgico de las Metástasis Hepáticas de Cáncer Colorectal. De las Resecciones Locales al Trasplante Hepático

et al. 2019

Rev. Cirugia

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El cáncer colorectal es de las principales causas de muerte por cáncer a nivel mundial. Una proporción importante de los casos desarrolla metástasis hepáticas. Gracias a los avances diagnósticos y tratamientos oncológicos, la sobrevida ha ido en aumento, sin embargo, para ello es fundamental lograr la resección quirúrgica completa de las lesiones primarias y metastásicas con márgenes microscópicos negativos (R0). Existen numerosos procedimientos y técnicas diseñadas para este objetivo como la quimioterapia neoadyuvante, embolización portal, cirugía en etapas, etc. A pesar de ello, hay casos no resecables por compromiso hepático bilobar, multisegmentario y/o compromiso de vasos arteriales, portales o venosos que en caso de resección, no permiten mantener hígado remanente funcional compatible con la vida del paciente. El trasplante hepático surge como alternativa radical para el tratamiento de casos no resecables. Dado la escasez de donantes y mortalidad en la lista de espera nacional, no es aceptable ocupar hígados del pool de donantes para patologías con criterios expandidos como metástasis colorectales. Sin embargo, con el recurso del donante vivo de adulto a adulto, hoy en día es posible indicar trasplante en casos seleccionados, que cumplan con todos los criterios establecidos.

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Parenchymal-sparing hepatectomies (PSH) for bilobar colorectal liver metastases are associated with a lower morbidity and similar oncological results: A propensity score matching analysis

Cited by 4 publications

References 29 publications

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

Primary Tumor Versus Liver‐First Approach for Synchronous Colorectal Liver Metastases: An Association Française de Chirurgie (AFC) Multicenter‐Based Study with Propensity Score Analysis

Tratamiento Quirúrgico de las Metástasis Hepáticas de Cáncer Colorectal. De las Resecciones Locales al Trasplante Hepático

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