“…To date, it is unclear how other-oriented feelings and related approach tendencies overcome initial self-oriented emotions and related avoidance. A potential key process might be the ability to regulate this self-oriented distress elicited by viewing another's pain 8,34,36 . In the present study, observers' distress is likely an automatic response to another's pain, which in later stages may be regulated by contextual and individual difference variables 32,35 , enabling other-oriented emotions to prevail 22,30,35,72,77 51 , it would be interesting to replicate the findings in participants with a close relationship, e.g.…”