Parental Hesitancy and Attitude Concerning COVID-19 Vaccine and Its Side Effects in Saudi Arabia, Eastern Region

Majzoub, Rabab A; Alrofaie, Omalbneen H; Almotreb, Lena K; Alateeq, Sarah K; Bin obaid, Fidaa R

doi:10.7759/cureus.48776

Cited by 2 publications

(1 citation statement)

References 30 publications

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“…As early as 2014, Sahin and colleagues had warned of the potential dangers of the mRNA vaccine technology, specifically cautioning that the encoded antigen should be investigated for multiple disease risks [131]. Surveys show that the primary concern expressed by parents regarding their children receiving the COVID-19 vaccines is not vaccine effectiveness but rather the potential AEs [132,133]. In a survey of US parents, concerns about the unprecedented speed of the mRNA vaccines' development (and, by implication, the rapid authorization process) were ranked just above concerns about harmful side effects [133].…”

Section: Analyses Of Serious Harms To Humansmentioning

confidence: 99%

COVID-19 mRNA Vaccines: Lessons Learned from the Registrational Trials and Global Vaccination Campaign

Mead,

Seneff,

Wolfinger

et al. 2024

Cureus

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Our understanding of COVID-19 vaccinations and their impact on health and mortality has evolved substantially since the first vaccine rollouts. Published reports from the original randomized phase 3 trials concluded that the COVID-19 mRNA vaccines could greatly reduce COVID-19 symptoms. In the interim, problems with the methods, execution, and reporting of these pivotal trials have emerged. Re-analysis of the Pfizer trial data identified statistically significant increases in serious adverse events (SAEs) in the vaccine group. Numerous SAEs were identified following the Emergency Use Authorization (EUA), including death, cancer, cardiac events, and various autoimmune, hematological, reproductive, and neurological disorders. Furthermore, these products never underwent adequate safety and toxicological testing in accordance with previously established scientific standards. Among the other major topics addressed in this narrative review are the published analyses of serious harms to humans, quality control issues and process-related impurities, mechanisms underlying adverse events (AEs), the immunologic basis for vaccine inefficacy, and concerning mortality trends based on the registrational trial data. The risk-benefit imbalance substantiated by the evidence to date contraindicates further booster injections and suggests that, at a minimum, the mRNA injections should be removed from the childhood immunization program until proper safety and toxicological studies are conducted. Federal agency approval of the COVID-19 mRNA vaccines on a blanket-coverage population-wide basis had no support from an honest assessment of all relevant registrational data and commensurate consideration of risks versus benefits. Given the extensive, well-documented SAEs and unacceptably high harm-to-reward ratio, we urge governments to endorse a global moratorium on the modified mRNA products until all relevant questions pertaining to causality, residual DNA, and aberrant protein production are answered.

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Section: Analyses Of Serious Harms To Humansmentioning

confidence: 99%

COVID-19 mRNA Vaccines: Lessons Learned from the Registrational Trials and Global Vaccination Campaign

Mead,

Seneff,

Wolfinger

et al. 2024

Cureus

View full text Add to dashboard Cite

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Eventos adversos da vacina contra COVID-19 em crianças e adolescentes: uma revisão integrativa

Klemann,

Freire,

Peres

et al. 2024

Rev enferm UFPE on line

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Objetivo: identificar os eventos adversos da vacina contra a COVID-19 em crianças e adolescentes (0-18 anos). Método: revisão integrativa, usando o referencial metodológico de Whittemore e Knalf, com Descritores em Ciências da Saúde (DeCS). Busca realizada nas bases de dados Scopus, CINAHL, Web of Science, Embase, PubMed e Biblioteca Virtual em Saúde, abrangendo o período de 2021 a 2022. Critérios de inclusão foram baseados na pergunta PICO. Resultados: analisaram-se 33 artigos de pesquisas, com níveis de evidência variando entre 3.c, 4.c e 4.d. As publicações abordaram os eventos adversos após a vacinação, ocorrendo de 24 horas a 27 dias após a administração, com média de nove dias. A maioria das ocorrências adversas foi observada em adolescentes do sexo masculino (42,4%) após a segunda dose. Cerca de 36,4% relataram eventos adversos após ambas as doses. Problemas cardíacos foram a principal preocupação (63,6%). Conclusão: os principais eventos adversos da vacinação contra a COVID-19 na população pediátrica identificados foram febre, dor torácica e mialgia, associados às complicações cardíacas. Apesar disso, as vantagens das vacinas contra a COVID-19 superam os seus riscos. O estudo é relevante para orientar a prática de enfermeiros na linha de frente dos processos vacinais e identificar possíveis eventos adversos.

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Parental Hesitancy and Attitude Concerning COVID-19 Vaccine and Its Side Effects in Saudi Arabia, Eastern Region

Cited by 2 publications

References 30 publications

COVID-19 mRNA Vaccines: Lessons Learned from the Registrational Trials and Global Vaccination Campaign

COVID-19 mRNA Vaccines: Lessons Learned from the Registrational Trials and Global Vaccination Campaign

Eventos adversos da vacina contra COVID-19 em crianças e adolescentes: uma revisão integrativa

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