Parental quality of life and depressive mood following methylphenidate treatment of children with attention‐deficit hyperactivity disorder

Abstract

Aim: This naturalistic study investigated the associations between quality of life and depressive mood in parents and symptom changes in attention-deficit hyperactivity disorder (ADHD) children. Methods:At baseline and at weeks 4 and 8, the parents evaluated their children, who were receiving treatment with osmotic-release oral system methylphenidate (mean dosage 36.3 ± 15.5 mg/day), using the Swanson, Nolan, and Pelham -Fourth Edition (SNAP-IV-18) scale. The parents evaluated themselves using the Beck Depression Inventory (BDI) and the World Health Organization Quality of Life Assessment, Brief Version (WHOQOL-BREF).Results: A significant reduction in SNAP-IV-18 scores and improvements in parental BDI scores and parental WHOQOL-BREF scores were observed. The decrease in BDI scores from baseline to 8 weeks was significantly associated with increases in WHOQOL-BREF sub-domain scores from baseline to 8 weeks, with a greater decrease at 4 weeks and after. The decrease in the SNAP-IV-18 hyperactivity-impulsivity score was significantly associated with increases in WHOQOL social sub-domain scores from baseline to 8 weeks. For those patients who showed a 25% or greater decrease in the SNAP-IV-18 total scores from baseline to 8 weeks, the decreases in the SNAP-IV-18 total score and in the inattention and hyperactivityimpulsivity scores were significantly associated with a decrease in BDI scores from baseline to 8 weeks. Conclusion:Methylphenidate treatment for ADHD was associated with both symptom alleviation in children with ADHD and improvement in parental depressive mood and quality of life, suggesting that the effects of treatment could go beyond symptom improvement in ADHD.

Quality of Life in Caregivers of ADHD Children and Diabetes Patients

“…In general terms, QoL may be thought of as a multidimensional construct incorporating an individual’s subjective perception of physical, emotional, and social well being, including both a cognitive (satisfaction) and an emotional component (happiness) ( 9 ). Although QoL is influenced by many proximal (e.g., family and friendship) and distal (e.g., socioeconomic and cultural) factors, the presence of a chronic illness has been considered as one of the most potent risk factors for worse QoL scores ( 4 , 9 – 14 ). Many authors have reported that chronic illnesses have an impact on many different aspects of the patient’s lives, which go beyond the core symptoms and impact their QoL ( 4 , 9 , 11 – 14 ).…”

“…Although QoL is influenced by many proximal (e.g., family and friendship) and distal (e.g., socioeconomic and cultural) factors, the presence of a chronic illness has been considered as one of the most potent risk factors for worse QoL scores ( 4 , 9 – 14 ). Many authors have reported that chronic illnesses have an impact on many different aspects of the patient’s lives, which go beyond the core symptoms and impact their QoL ( 4 , 9 , 11 – 14 ). In studies using the World Health Organization Quality of Life-Bref Form (WHOQOL-Bref), one of the most used instruments to assess QoL, the scores are frequently lower in patients with chronic diseases, such as diabetes ( 9 , 15 – 17 ).…”

“…Some studies have also demonstrated the association between the presence of chronic mental and physical disorders and QoL impairment ( 11 , 14 , 22 – 26 ). For instance, Akvardar et al compared the QoL scores in three samples: (a) patients with psychiatric disorders, (b) diabetic patients, and (c) controls ( 24 ).…”

Predictors of Burden of Care Among Caregivers of Drug-Naive Children and Adolescents With ADHD: A Cross-Sectional Correlative Study From Muscat, Oman

“…ADHD needs to be understood and managed within a biopsychosocial paradigm that gives cognizance to the interaction between biological, psychological, and social variables [47] particularly those impacting the quality of relationship between the caregiver and the child. of life [48][49][50][51], psychological disorders [52]. These studies do suggest that caregivers of children with ADHD tend to endorse high levels of burden compared to controls [53].…”

Differences in Utilization Patterns among Medications in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: a 36-Month Retrospective Study Using the Korean Health Insurance Review and Assessment Claims Database

“…In previous studies, the discontinuation of ADHD medications has been associated with suboptimal control of symptoms, increasing the likelihood of harmful and serious behaviors including social adversity, academic difficulties, behavioral problems, and poor economic, social, and emotional well-being ( 28 29 30 ). In addition, family and associated community members can be influenced by these adverse consequences as well ( 31 32 ), which could not be measured in the current study because the data from the Korean HIRA claims database were not allowed to link with any information of their family members. In previous studies, changes in parenting stress and parental quality of life were measured during the 8-week treatment with OROS-MPH in children and adolescents with ADHD.…”