Parental Smoking, Presence of Older Siblings, and Family History of Asthma Increase Risk of Bronchiolitis

McConnochie, Kenneth M.

doi:10.1001/archpedi.1986.02140220088039

Cited by 105 publications

(87 citation statements)

References 33 publications

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“…Infants and young children are at particular risk of exposure to ETS because of the small diameter of their airways and because pound-forpound they breathe more air than adults. Infants exposed to ETS in their home environment have a 1.5-to 3-fold increased risk of lower respiratory infection compared with unexposed children (McConnochie and Roghmann 1986;Ogston et al 1987;). The risk of lower respiratory infection associated with ETS is highest among infants under 3 months of age .…”

Section: Risks At Different Agesmentioning

confidence: 99%

Children's health and the environment: public health issues and challenges for risk assessment.

Landrigan

Kimmel

Correa

et al. 2004

Environ Health Perspect

368

206

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Infants and children are not little adults. They are uniquely vulnerable to environmental toxicants. To protect infants and children against toxicants, the National Research Council in 1993 called for development of an approach to risk assessment that considers children's unique patterns of exposure and their special vulnerabilities to pesticides. Many aspects of that call were codified into federal law in the Food Quality Protection Act (FQPA) of 1996. This report highlights the central elements needed for development of a child-protective approach to risk assessment: a) improved quantitative assessment of children's exposures at different life stages, from fetal life through adolescence, including acute and chronic exposures, exposures via multiple routes, and exposures to multiple agents; b) development of new approaches to toxicity testing of chemicals that can detect unanticipated and subtle outcomes and that evaluate experimental subjects over the entire life span from early exposure to natural death to replicate the human experience; c) development of new toxicodynamic and toxicokinetic models that account for the unique physiologic characteristics of infants and children; d) development of new approaches to assessment of outcomes, functional, organ, cellular and molecular, over the entire life span; these measures need to be incorporated into toxicity testing and into long-term prospective epidemiologic studies of children; and e) application of uncertainty and safety factors in risk assessment that specifically consider children's risks. Under FQPA, children are presumed more vulnerable to pesticides than adults unless evidence exists to the contrary. Uncertainty and safety factors that are protective of children must therefore be incorporated into risk assessment when data on developmental toxicity are lacking or when there is evidence of developmental toxicity. The adequate protection of children against toxic agents in the environment will require fundamental and far-reaching revisions of current approaches to toxicity testing and risk assessment.

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Section: Risks At Different Agesmentioning

confidence: 99%

Children's health and the environment: public health issues and challenges for risk assessment.

Landrigan

Kimmel

Correa

et al. 2004

Environ Health Perspect

368

206

View full text Add to dashboard Cite

show abstract

“…Foi evidenciado o efeito da aglomeração familiar em outros estudos (10,43,45) . Fumo passivo, irmãos mais velhos e aglomeração foram, estatisticamente, significantes como preditores de bronquiolites (44) .…”

Section: Discussionunclassified

Morbidade respiratória em crianças fumantes passivas

Carvalho¹,

Pereira²

2002

J. Pneumologia

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Objetivo:Objetivo: Avaliar a prevalência de morbidade respiratória entre crianças expostas ao fumo passivo e determinar os efeitos do fumo ambiental no sistema respiratório inferior e superior dessas crianças, na cidade de Fortaleza, Ceará, Brasil. Respiratory morbidity among passive smoking children Objective: Objective: To study the prevalence of respiratory morbidity among passive smoking children and to determine the effects of environmental tobacco smoke in the upper and lower respiratory system of these children in the city of Fortaleza, Ceará, Brazil. Cases and method:Cases and method: This is a cross sectional study of 1,104 children under the 5 years old. Information about respiratory symptoms and illnesses of the children, family history of respiratory diseases, smoking habits of household members and housing conditions were assessed by a questionnaire addressed to the children's parents. Results:Results: Among the 1,104 children, 558 were males and 546 were females. Respiratory morbidity was greater in the children exposed to environmental tobacco smoke than in those who were not exposed (82% vs 74%). Regarding the lower respiratory tract, the most frequent complaints were wheeze (57.7%; OR = 1.32; IC 95%: 1.04-1.68), dyspnea (43.8%; OR = 1.56; IC 95%: 1.22-1.99), asthma, bronchitis or pneumonia (29.4%; OR = 1.31; IC 95%: 1.00-1.71).As to the upper respiratory tract, rhinitis was the most frequent complaint (38.1%; OR = 1.46;ARTIGO ORIGINAL

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“…O diagnóstico de bronquiolite foi baseado em achados clínicos, incluindo os seguintes: sibilância expiratória de início agudo, ausência de história prévia, sinais de doença respiratória viral -tais como: coriza, tosse ou febre -acompanhados de dificuldade respiratória (Mcconnochie & Roghmann, 1984, 1985, 1986Morris et al, 1990;Mulholland et al, 1990;Skoner et al,1990;Murray et al, 1992;Sung et al, 1992;Sigurs et al, 1995). Sibilância recorrente foi definida como duas ou mais crises de chiado no peito que causassem falta de ar, cansaço ou dificuldade para respirar.…”

Section: Critério Diagnósticounclassified

Hospitalização por bronquiolite aguda como fator de risco para sibilância recorrente

et al. 2000

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Parental Smoking, Presence of Older Siblings, and Family History of Asthma Increase Risk of Bronchiolitis

Cited by 105 publications

References 33 publications

Children's health and the environment: public health issues and challenges for risk assessment.

Children's health and the environment: public health issues and challenges for risk assessment.

Morbidade respiratória em crianças fumantes passivas

Hospitalização por bronquiolite aguda como fator de risco para sibilância recorrente

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