Parenteral iron therapy in children with iron deficiency anemia: A single‐institution experience

Abstract

To the Editor, Oral iron is the preferred route of supplementation for iron deficiency and iron deficiency anemia (IDA) in all age groups. In patients who do not tolerate or adhere to oral formulations, parenteral iron supplementation may be warranted. Studies on the efficacy and safety of intravenous (IV) iron in children with IDA are lacking. [1][2][3][4][5][6] Moreover, concerns about severe adverse reactions, such as life-threatening hypersensitivity, contribute to the avoidance of IV iron therapy in pediatric practice. 7 Faced with persistent underuse of parenteral iron, we conducted a retrospective study of 61 patients with IDA who were consecutively

Reply to: Comment on: Intravenous iron for critically ill children. Comparison of three dose regimens

“…7 Regarding the significance of Hb levels improvement in our cohort, other non-RCT reports in pediatric patients describe similar or greater Hb increases. [8][9][10][11][12][13][14] Also, commentators query about the possibility of dilutional anemia at admission in post-surgical patients.…”