“…89 Most of the data on children have been derived from studies of hospitalized premature or newborn infants. An increased risk of IF/PNALD was associated with young gestational age, 90 91,103 An appropriate PN regimen is also important as high parenteral energy intake, 88,95,104 use of a soybean-based lipid emulsion at a dose of >1 g/kg, 53 dextrose infusion >7 mg/ kg/min, 84,105 high amino acid load in premature infants, 90 as well as deficiency of transsulfuration pathway products, most notably choline, 106 have been reported to favour the development of IF/ PNALD. The use of lipid emulsion with a low content of omega-6 fatty acids is recommended both in preventing and treating IF/ PNALD.…”