Parinaud's oculoglandular syndrome associated with Sporothrix schenckii

Ferreira, Cássio Porto; Nery, José Augusto daCosta; Almeida, Ana Cristina Oliveira de; Ferreira, Luíz Cláudio; Cortê-Real, Suzana; Conceição-Silva, Fátima

doi:10.1016/j.idcr.2014.05.001

Cited by 15 publications

(13 citation statements)

References 10 publications

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“…The simultaneous affection of the ocular mucosa and the regional lymph nodes is not rare, and it is one of the causes of the Parinaud syndrome. 58 …”

Section: Clinical Aspectsmentioning

confidence: 99%

Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics

Orofino-Costa

Macedo

Rodrigues

et al. 2017

An. Bras. Dermatol.

279

397

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In the late 90's there was a change in both the route of transmission and the people at risk for sporotrichosis. This zoonotic cat-man alternative transmission route elicited changes in strategies to control the epidemic. There was a progressive increase in the number of cases involving especially children and the elderly. In addition to becoming hyperendemic, uncommon clinical pictures like immunoreactive clinical presentations or severe systemic cases have emerged. New species were identified and classified through molecular tools using more virulent clinical isolates, like S. brasiliensis, compared to the environmental isolates. Likewise, different species of Sporothrix have been associated with different geographic regions. The serological and molecular techniques are used as an auxiliary tool for the diagnosis and/or for species identification, although the isolation and the identification of Sporothrix spp. in clinical specimen is still the gold standard. Currently sporotrichosis epidemics requires the knowledge of the epidemiological-molecular profile to control the disease and the specific treatment. Itraconazole, potassium iodide, terfinafine, and amphotericin B are the available drugs in Brazil to treat sporotrichosis. The drug of choice, its posology, and treatment duration vary according to the clinical presentation, the Sporothrix species, and host immune status. New treatment choices, including a vaccine, are being developed; nevertheless, more clinical trials are required to confirm its efficacy.

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“…The simultaneous affection of the ocular mucosa and the regional lymph nodes is not rare, and it is one of the causes of the Parinaud syndrome. 58 …”

Section: Clinical Aspectsmentioning

confidence: 99%

Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics

Orofino-Costa

Macedo

Rodrigues

et al. 2017

An. Bras. Dermatol.

279

397

View full text Add to dashboard Cite

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“…The lesions are granulomatous, ulcerous and painful. The simultaneous affection of the ocular mucosa and the regional lymph nodes is not rare, and it is one of the causes of Parinaud syndrome [ 6 , 7 , 8 ].…”

Section: Clinical Diagnosismentioning

confidence: 99%

“…The differential diagnosis of cutaneous disease includes other infection and non-infection lesions that look alike verrucous tuberculosis, atypical mycobacterial infection, leprosy, mycetoma, chromoblastomycoses or squamous cell carcinoma. In case of pulmonary involvement differential diagnosis with tuberculosis is mandatory [ 3 , 7 , 11 ].…”

Section: Clinical Diagnosismentioning

confidence: 99%

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Sporotrichosis: From KOH to Molecular Biology

Arenas

Sánchez-Cárdenas

Ramírez-Hobak

et al. 2018

JoF

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“…Sporotrichosis may manifest as Parinaud oculoglandular syndrome, which is characterized by granulomatous conjunctivitis associated with preauricular and submandibular lymphadenopathy. 5 …”

Section: Introductionmentioning

confidence: 99%

Ocular Sporotrichosis

Ribeiro¹,

Silva²,

Costa³

et al. 2020

American Journal of Ophthalmology Case Reports

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Purpose To present 10 cases of Parinaud oculoglandular syndrome caused by sporotrichosis. Observations We report 10 cases of Parinaud oculoglandular syndrome after contact with domestic cats diagnosed with sporotrichosis. They all showed ocular hyperemia associated with unilateral tarsal conjunctival granulomas. After histopathological study and culture of the scrapings and conjunctival secretions, six patients were positive for Sporothrix schenkii and four had a presumed diagnosis of Parinaud oculoglandular syndrome due to sporotrichosis. Treatment with 200 mg/day of oral itraconazole was started, and all patients had a favorable therapeutic response. Conclusion and importance These case reports are essential for characterizing a rare etiology of Parinaud oculoglandular syndrome.

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Parinaud's oculoglandular syndrome associated with Sporothrix schenckii

Cited by 15 publications

References 10 publications

Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics

Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics

Sporotrichosis: From KOH to Molecular Biology

Ocular Sporotrichosis

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