Parity and vitamin D metabolites

Moghraby, Salah; Shawaf, Turke; Akiel, Abdullah S.; Sedrani, Saleh H.; Idrissy, A. T. H. El; Al-Meshari, Abdulaziz

doi:10.1080/02724936.1987.11748509

Cited by 10 publications

(7 citation statements)

References 10 publications

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“…12 Parity was specifically studied in 86 Saudi pregnant women; however, the authors compared patients who were para 5 to subjects who were para 4 or less, and in this comparison, parity did not affect vitamin D levels. 26 In our population, primigravid women may have different habits than multiparous women. We did not examine the relationship of parity to diet, sun exposure, and supplementation use in this analysis.…”

Section: Discussionmentioning

confidence: 88%

Vitamin D Deficiency and Insufficiency is Common during Pregnancy

Johnson

Wagner²,

Hulsey³

et al. 2010

Amer J Perinatol

166

129

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The objective was to determine the incidence of vitamin D deficiency, insufficiency, and sufficiency in African-American, Hispanic, and Caucasian pregnant women. Blood samples were taken from 154 African-American, 194 Hispanic, and 146 Caucasian women at <14 weeks of gestation; 25 hydroxyvitamin D levels (25(OH)D) levels were measured by radioimmunoassay. The mean 25(OH)D levels in African-American, Hispanic, and Caucasian pregnant women were 15.5 ± 7.2 (standard deviation), 24.1 ± 8.7, 29.0 ± 8.5 ng/mL, respectively. Ninety-seven percent of African-Americans, 81% of Hispanics, and 67% of Caucasians were deficient (25(OH)D levels <20 ng/mL or <50 nmol/L) or insufficient (25(OH)D levels ≥ 20 ng/mL or <32 ng/mL or ≥ 50 nmol/L or <80 nmol/L). Of these pregnant women, 82% had vitamin D levels <32 ng/mL (<80 ng/mL). In logistic regression models, race was the most important risk factor for vitamin D deficiency or insufficiency. African-American women and Hispanic women were more likely to have vitamin D insufficiency and deficiency than Caucasian women. Furthermore, primigravid women were more at risk for vitamin D insufficiency. This study demonstrates widespread vitamin D deficiency and insufficiency in pregnant females living at a southern latitude. African-Americans are at greatest risk.

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Section: Discussionmentioning

confidence: 88%

Vitamin D Deficiency and Insufficiency is Common during Pregnancy

Johnson

Wagner²,

Hulsey³

et al. 2010

Amer J Perinatol

166

129

View full text Add to dashboard Cite

show abstract

“…2,3,8,9 Many of the mothers and children in this study had reportedly taken locally made dairy products which were not forti ed with vitamin D. After this study was completed, efforts were initiated to encourage fortifying local dairy produce with vitamin D.…”

Section: Discussionmentioning

confidence: 97%

“…2,3 There is also evidence of vitamin C de ciency in UAE mothers. 4 Furthermore, serum vitamin C and 25-hydroxyvitamin D (a measure of body vitamin D stores) are low at birth in infants born to UAE nationals and other Arab mothers.…”

Section: Introductionmentioning

confidence: 97%

Diet, clothing, sunshine exposure and micronutrient status of Arab infants and young children

et al. 2001

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Vitamin C and D levels in Arab women and their newborn infants have been shown to be low. We investigated the prevalence of and risk factors for possible hypovitaminosis C and D in a convenience sample of 51 hospitalized children without clinical features of vitamin C or D deficiency. The mean age was 15.4 months. The serum vitamin C concentration was low in the mothers but normal in the children. Both mothers and children had low serum 25-hydroxyvitamin D (25-OHD) concentrations. Fifty per cent of the mothers and 22% of the infants and children had hypovitaminosis D (serum 25-OHD level < 25 nmol/l). Infants who received dietary vitamin D supplementation had a higher mean (SD) serum 25-OHD concentration than the unsupplemented group (62.5 (29.8) vs 38.5 (27.3), p = 001). Cutaneous light exposure in these children was poor. The children's serum 25-OHD concentration correlated with dietary vitamin D supplementation and maternal serum 25-OHD levels. The results suggest normal vitamin C status but a possible high prevalence of hypovitaminosis D in Arab children and their mothers in UAE. Health education to encourage greater sunshine exposure and improvement in maternal vitamin D stores and the availability of adequate vitamin D supplements would improve children's vitamin D status. The study indicates that hypovitaminosis D continues to be an important maternal and child health problem, despite the abundant sunshine.

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“…We have demonstrated normal or high levels of l,25(OH)2D in pregnancy in spite of the low levels of 25-OHD, 38 and lack of correlation between the two metabolites was shown. 39 In our series, even in extremely low 25-OHD levels among pregnant women, no infant was reported as born with clinical evidence of rickets 31 but there was a high incidence of neonatal hypocalcemia. 30 High parity was not found to be a factor in the low maternal vitamin D status.…”

Section: Maternal Vitamin D Deficiency Causing Rickets In Infantsmentioning

confidence: 90%

“…30 High parity was not found to be a factor in the low maternal vitamin D status. 30,39 The active transplacental calcium transfer in spite of poor vitamin D status of the mother was found to maintain adequate fetal bone mineralization and prevent congenital rickets except in states of severe maternal osteomalacia. 40 The maternal vitamin-D-deficiency state during pregnancy leads to delivery of infants with poor vitamin D stores.…”

Section: Maternal Vitamin D Deficiency Causing Rickets In Infantsmentioning

confidence: 99%

Vitamin D Deficiency Rickets in a Sunny Country: Pathogenesis, Clinical Picture and Management

Elidrissy

1987

Ann Saudi Med

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Vitamin D deficiency rickets occurs in sunny countries, mainly due to man-made environmental factors associated with avoidance of sunshine. This situation can be prevented by more health education regarding exposure to sunshine. Designs of houses in urban areas need to be changed to allow for such exposure while still maintaining privacy. Fortification of foods with vitamin D is not without hazards and need not be advocated, but the risk groups can be given vitamin D supplementation in physiological doses. The tragic effects of vitamin D intoxication must be always borne in mind when prescribed as prophylaxis in massive doses. Finally, vitamin D deficiency diseases can be eradicated by more exposure to the sun. Country: Pathogenesis, Clinical Picture and Management. 1987; 7(2): 119-125 MeSH ATH Elidrissy, Vitamin D Deficiency Rickets in a Sunny

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Parity and vitamin D metabolites

Cited by 10 publications

References 10 publications

Vitamin D Deficiency and Insufficiency is Common during Pregnancy

Vitamin D Deficiency and Insufficiency is Common during Pregnancy

Diet, clothing, sunshine exposure and micronutrient status of Arab infants and young children

Vitamin D Deficiency Rickets in a Sunny Country: Pathogenesis, Clinical Picture and Management

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