Parkinson's disease.

Marsden, C. D.

doi:10.1136/jnnp.57.6.672

Cited by 362 publications

(184 citation statements)

References 104 publications

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“…Frontal lobe dysfunction in PD dementia has been documented in many clinical studies, although both the clinical signs and degree of atrophy differ significantly from that occurring in the frontotemporal degenerative dementias [34,35], Frontal deficits in PD are often more marked in older patients [4,25,36], and mild or absent in nondemented PD patients [1,37], The mild frontal lobe atrophy noted in our late-onset PD cases may be the ana tomical substrate for such a difference. The late-onset PD cases had significant cortical plaque pathology compared with controls and middle-age-onset cases but were with out cortical neuronal pathology.…”

Section: Climcopathological Correlationsmentioning

confidence: 66%

Regional Brain Atrophy in Idiopathic Parkinson's Disease and Diffuse Lewy Body Disease

Double

Halliday²,

Mcritchie³

et al. 1996

Dement Geriatr Cogn Disord

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This study measured brain atrophy in patients with idiopathic Parkinson''s disease and diffuse Lewy body disease, all of whom had equivalent loss of midbrain dopaminergic neurons and absence of Alzheimer''s disease. Characteristic patterns of volume loss were found throughout the brain, depending on the age of onset and clinical signs. An equivalent loss of medial temporal lobe structures occurred in all parkinsonian patients. This atrophy was similar in magnitude to that seen in Alzheimer''s disease and is likely to be the anatomical substrate for the memory deficits found in each of these patient groups. Frontal lobe atrophy was a feature of both late-onset Parkinson''s disease (mild atrophy) and diffuse Lewy body disease (significant atrophy) groups, with all cases analyzed having dementia. Atrophy of frontal lobes correlated with the duration of motor symptoms in these patients and may suggest an association between dopaminergic deafferentation, frontal atrophy and dementia.

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Section: Climcopathological Correlationsmentioning

confidence: 66%

Regional Brain Atrophy in Idiopathic Parkinson's Disease and Diffuse Lewy Body Disease

Double

Halliday²,

Mcritchie³

et al. 1996

Dement Geriatr Cogn Disord

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“…Our data also give the first information about the bioelectrical characteristics of the PD patients in Slovakia. Parkinson´s disease (PD) is a common neurodegenerative disease, leading to primary degeneration of the nigrostriatal system [20]. Except for motor features of PD subjects, the non-motor symptoms, in some cases, can dominate the clinical picture.…”

Section: Discussionmentioning

confidence: 99%

Bioelectrical Impedance Vector Analysis (BIVA) in Slovak population: application in a clinical sample

et al. 2013

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The purpose of this study is to provide new data on body composition in the Slovak population, particularly impedance vector components according to sex and age, relevant for bioelectrical impedance vector analysis (BIVA) in a clinical sample. The reference sample consisted of 1543 apparently healthy individuals (1007 females and 536 males), aged from 18 to 92 years and of 60 patients with Parkinson’s disease (PD) (26 females and 34 males), aged from 40 to 81 years. Bioelectrical parameters of resistance (R) and reactance (Xc) were measured with a monofrequency analyser (BIA 101). BIVA was used to analyse tissue electric properties in control subjects and patients with PD. The mean vector position differed significantly between PD patients and healthy controls in males of age subgroups 60–69 years and 70–79 years, respectively. These results were conterminous with significant Hotelling’s T2-test; 60–69 y T2=7.8, P=0.024 and 70–79 y T2=7.6, P=0.026. In the RXc-score graph three patients had values outside the 95% ellipse. Altered tissue electric properties were present in 23.5% of males and 15.4% of females. Distribution of impedance vector components in different age categories of healthy Slovak subjects are relevant to comparative population studies and to clinical practice.

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“…Os critérios de elegibilidade comuns a todos os participantes foram: ausência de dor, fratura, ou lesão grave em tecidos moles nos 6 meses pregressos ao estudo, bem como histórico de alterações cognitivas, cardiovasculares ou respiratórias [9]. Para a avaliação da função cognitiva foi utilizado o Mini Exame do Estado Mental e foram excluídos do estudo os pacientes que apresentarem score < 24 [10].…”

Section: Materiais E Métodosunclassified

Análise Eletromiográfica Da Marcha De Pacientes Em Diferentes Estágios Da Doença De Parkinson

Brbara¹,

Lucas²,

Kennedy³

et al. 2018

Anais Do v Congresso Brasileiro De Eletromiografia E Cinesiologia E X Simpósio De Engenharia Biomédica

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Parkinson's disease.

Cited by 362 publications

References 104 publications

Regional Brain Atrophy in Idiopathic Parkinson's Disease and Diffuse Lewy Body Disease

Regional Brain Atrophy in Idiopathic Parkinson's Disease and Diffuse Lewy Body Disease

Bioelectrical Impedance Vector Analysis (BIVA) in Slovak population: application in a clinical sample

Análise Eletromiográfica Da Marcha De Pacientes Em Diferentes Estágios Da Doença De Parkinson

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