Parkinson???s Disease, Macular Degeneration and Cutaneous Signs of Mercury Toxicity.

Dantzig, Paul I.

doi:10.1097/01.jom.0000228351.74230.52

Cited by 24 publications

(13 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Early evidence had indicated a biochemical and electrophysiological disorder in the retina in PD patients (Nightingale et al, 1986). Today, it has even been suggested that PD and macular degeneration may have a common etiology (Dantzig, 2006). Some works suggested that the evidence favored the retina as one, if not the site of visual dysfunction in PD (Dyer et al, 1981;Bodis-Wollner and Tagliati, 1993) and that primary visual dysfunction may even contributed to visuocognitive manifestations of the disease process, and to the locomotor and postural disabilities (Masson et al, 1993).…”

Section: Visual Deficits In Pdmentioning

confidence: 98%

The possible role of retinal dopaminergic system in visual performance

Brandies

Yehuda

2008

Neuroscience & Biobehavioral Reviews

View full text Add to dashboard Cite

Section: Visual Deficits In Pdmentioning

confidence: 98%

The possible role of retinal dopaminergic system in visual performance

Brandies

Yehuda

2008

Neuroscience & Biobehavioral Reviews

View full text Add to dashboard Cite

“…Elemental mercury has induced PD [175], and in a case report, the condition of PD substantially improved after treatment with a mercury chelator [173] and remained unchanged during a 5-year follow-up period [173]. In another study, significantly elevated blood mercury levels were found in 13 of 14 patients with PD compared to healthy controls [172]. This supports the conclusion of a previous study which found a correlation between blood mercury levels and PD [176].…”

Section: Parkinson's Disease (Pd)mentioning

confidence: 99%

Is dental amalgam safe for humans? The opinion of the scientific committee of the European Commission

Mutter¹

2011

J Occup Med Toxicol

View full text Add to dashboard Cite

It was claimed by the Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR)) in a report to the EU-Commission that "....no risks of adverse systemic effects exist and the current use of dental amalgam does not pose a risk of systemic disease..." [1, available from: http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_016.pdf].SCENIHR disregarded the toxicology of mercury and did not include most important scientific studies in their review. But the real scientific data show that:(a) Dental amalgam is by far the main source of human total mercury body burden. This is proven by autopsy studies which found 2-12 times more mercury in body tissues of individuals with dental amalgam. Autopsy studies are the most valuable and most important studies for examining the amalgam-caused mercury body burden.(b) These autopsy studies have shown consistently that many individuals with amalgam have toxic levels of mercury in their brains or kidneys.(c) There is no correlation between mercury levels in blood or urine, and the levels in body tissues or the severity of clinical symptoms. SCENIHR only relied on levels in urine or blood.(d) The half-life of mercury in the brain can last from several years to decades, thus mercury accumulates over time of amalgam exposure in body tissues to toxic levels. However, SCENIHR state that the half-life of mercury in the body is only "20-90 days".(e) Mercury vapor is about ten times more toxic than lead on human neurons and with synergistic toxicity to other metals.(f) Most studies cited by SCENIHR which conclude that amalgam fillings are safe have severe methodical flaws.

show abstract

“…In fact, mercury has not only been associated with the incidence of PD, but several similarities between the effects of mercury exposure/ingestion, and the symptoms/consequences of PD have been identified ( Table 1). Detectable blood mercury levels were six times more frequent in individuals with PD than in healthy controls [78]. In another larger study, significantly higher blood Hg levels were seen in PD patients compared to controls, and mercury exposure was associated with an 8-fold increase in the risk of developing PD [57].…”

Section: Mercurymentioning

confidence: 87%

Metals and Parkinson's Disease: Mechanisms and Biochemical Processes

Bjørklund

Stejskal²,

Urbina

et al. 2018

CMC

139

View full text Add to dashboard Cite

Genetic background accounts for only 5 to 10% of the reported cases of Parkinson's disease (PD), while the remaining cases are of unknown etiology. It is believed that environmental factors may be involved in the causality of a large proportion of PD cases. Several PD genes are activated by xenobiotic exposure, and a link between pesticide exposure and PD has been demonstrated. Many epidemiological studies have shown an association between PD and exposure to metals such as mercury, lead, manganese, copper, iron, aluminum, bismuth, thallium, and zinc. This review explores the biological effects, the pathogenetic processes, genetic susceptibilities to metals as well as examining future strategies for PD treatment, such as chelation therapy.

show abstract

Parkinson???s Disease, Macular Degeneration and Cutaneous Signs of Mercury Toxicity.

Abstract: Mercury may play a role in the etiology of Parkinson disease and Grover's disease.

Cited by 24 publications

References 5 publications

The possible role of retinal dopaminergic system in visual performance

The possible role of retinal dopaminergic system in visual performance

Is dental amalgam safe for humans? The opinion of the scientific committee of the European Commission

Metals and Parkinson's Disease: Mechanisms and Biochemical Processes

Contact Info

Product

Resources

About