Parkinsonism due to Coxsackie B Virus Infection—Case Report and Literature Review

Vlad, Benjamin; Jelcic, Ilijas; Balint, Bettina

doi:10.1002/mdc3.13773

Cited by 3 publications

(2 citation statements)

References 13 publications

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“…During the acute phase of EL, sleep, ocular motility, and movement disorders are typically related, whereas in the chronic phase, parkinsonism (a term used to describe syndromes similar to Parkinson's Disease, which emerge as an immediate sequela to viral encephalitis) can be observed ( Berger and Vilensky, 2014 ; Jang et al, 2009 ). Reports of the disease throughout the world show that some CV types, particularly CVB1-B4 may produce a post-encephalitic syndrome of acute parkinsonism ( Cree et al, 2003 ; Jang et al, 2009 ; Walters, 1960 ; Poser et al, 2009 ; Peatfield, 1987 ; Vlad et al, 2023 ).…”

Section: Cv-associated Infectionsmentioning

confidence: 99%

Global landscape of coxsackieviruses in human health

Machado,

Tavares,

Sousa

2024

Virus Research

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Section: Cv-associated Infectionsmentioning

confidence: 99%

Global landscape of coxsackieviruses in human health

Machado,

Tavares,

Sousa

2024

Virus Research

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“…The presented cases cover a very broad spectrum of movement disorders and etiologies, including neurogenetic, infectious, drug‐induced, metabolic, tumor‐related, and autoimmune causes. 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 Importantly, they provide practical take‐home messages and clues to diagnosis, as means to optimize the level of care for our patients.…”

mentioning

confidence: 99%

Preface to the 4th MDS Video Challenge Case Supplement for Movement Disorders Clinical Practice

Matarazzo,

Ganos

2023

Movement Disord Clin Pract

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Infections in the Etiology of Parkinson’s Disease and Synucleinopathies: A Renewed Perspective, Mechanistic Insights, and Therapeutic Implications

Mercado,

Kaeufer,

Richter

et al. 2024

Journal of Parkinson’s Disease

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Increasing evidence suggests a potential role for infectious pathogens in the etiology of synucleinopathies, a group of age-related neurodegenerative disorders including Parkinson’s disease (PD), multiple system atrophy and dementia with Lewy bodies. In this review, we discuss the link between infections and synucleinopathies from a historical perspective, present emerging evidence that supports this link, and address current research challenges with a focus on neuroinflammation. Infectious pathogens can elicit a neuroinflammatory response and modulate genetic risk in PD and related synucleinopathies. The mechanisms of how infections might be linked with synucleinopathies as well as the overlap between the immune cellular pathways affected by virulent pathogens and disease-related genetic risk factors are discussed. Here, an important role for α-synuclein in the immune response against infections is emerging. Critical methodological and knowledge gaps are addressed, and we provide new future perspectives on how to address these gaps. Understanding how infections and neuroinflammation influence synucleinopathies will be essential for the development of early diagnostic tools and novel therapies.

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Parkinsonism due to Coxsackie B Virus Infection—Case Report and Literature Review

Cited by 3 publications

References 13 publications

Global landscape of coxsackieviruses in human health

Global landscape of coxsackieviruses in human health

Preface to the 4th MDS Video Challenge Case Supplement for Movement Disorders Clinical Practice

Infections in the Etiology of Parkinson’s Disease and Synucleinopathies: A Renewed Perspective, Mechanistic Insights, and Therapeutic Implications

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