Parkinsonism in Caplan’s syndrome

Abstract

Parkinsonism is a rare feature of immunological diseases. We describe a 67-year-old man with Caplan's syndrome (CS) and parkinsonism. CS is an immunologic disease characterised by the presence of rheumatoid arthritis associated with a specific form of pneumoconiosis. Parkinsonism as a manifestation of involvement of the central nervous system in this condition has never been reported. Following immunosuppressive treatment both the CS and the parkinsonian signs and symptoms showed a marked improvement. The role of immune mechanisms in these parkinsonian syndromes is discussed.

DaT Scan “Abnormality” in Hyperglycemic-Hemichorea

“…6 However, when MRI signal abnormalities are present in the basal ganglia, DaT scan results must be interpreted with caution. 8 Some reported cases in the literature [9][10][11][12][13] attribute parkinsonism due to abnormal DaT scan despite abnormality on structural imaging. It is therefore imperative that the results of DaT scan are interpreted in the context of structural imaging findings.…”

Response Letter: Paraneoplastic Chorea Managed with Intravenous Amantadine

“…3 There are many examples in literature of structural imaging abnormalities in the striatum with corresponding decreased uptake while using DaT scan techniques. 4–8 It is important to stress that obtaining DaT scan imaging on a routine basis in patients diagnosed with structural abnormalities in the striatum upon conducting MRI is generally not indicated and can expose patients to unnecessary risk.…”

Paraneoplastic Chorea Managed with Intravenous Amantadine

“…3 There are many examples in literature of structural imaging abnormalities in the striatum with corresponding decreased uptake while using DaT scan techniques. [4][5][6][7][8] It is important to stress that obtaining DaT scan imaging on a routine basis in patients diagnosed with structural abnormalities in the striatum upon conducting MRI is generally not indicated and can expose patients to unnecessary risk.…”