Parosteal osteosarcoma with focal fatty metaplasia: A case report

Abstract

Parosteal osteosarcoma originates on the surface of long bones. The juxtacortical variety is one of the most common ones and accounts for about 5% of all osteosarcomas. We report the case of a 34-year-old female patient with a rare variant of parosteal osteosarcoma. Because of the less aggressive biological behavior, it is important to know it, in order to recognize and differentiate it from benign osseous lesions.

Sarcomas of fat and bone: a case report

“…Liposarcomas of bone (also titled osteoliposarcomas or malignant mesenchymomas) were initially reported in 1934 [10]. They are quite rare, most are reported to be pleomorphic and as far as they have been analyzed they were reported MDM2 and CDK4 negative [11,12]. Liposarcomas with osteogenic differentiation are well known and fall in the category of dedifferentiated liposarcoma, the two most common forms of heterologous differentiation in dedifferentiated liposarcoma are myogenic and osteosarcomatous/chondrosarcomatous [13], they show MDM2 amplification.…”