Parotid and parapharyngeal tumours: tissue characterization with dynamic magnetic resonance imaging

Tsushima, Yoshito; Matsumoto, M; Endo, K

doi:10.1259/0007-1285-67-796-342

Cited by 54 publications

(36 citation statements)

References 3 publications

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“…One of the reasons for the inconsistencies among past studies might be their small sample sizes; with one exception, 6 each analysed only 20-50 cases. [8][9][10][11][12][13][14][15][17][18][19][20] Another reason may be the differences in imaging protocols used to obtain DCE-MRI data sets. For obtaining accurate TICs, dynamic sequences with high temporal resolutions should be applied.…”

Section: Discussionmentioning

confidence: 99%

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Differentiating benign and malignant salivary gland tumours: diagnostic criteria and the accuracy of dynamic contrast-enhanced MRI with high temporal resolution

Lam¹,

Kuribayashi²,

Imaizumi³

et al. 2015

BJR

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The authors Phong Dai Lam and Ami Kuribayashi equally contributed to this work.Objective: To determine the optimal diagnostic criterion of dynamic contrast-enhanced MRI (DCE-MRI) for predicting salivary gland malignancy using a dynamic sequence with high temporal resolution, as well as the accuracy of this technique. Methods: The DCE-MRI findings of 98 salivary gland tumours (74 benign and 24 malignant) were reviewed. MR images were sequentially obtained at 5-s intervals for 370 s. Two parameters, peak time and washout ratio (WR) were determined from the time-signal intensity curve. The optimal thresholds of these parameters for differentiating benign and malignant tumours were determined, along with the diagnostic accuracy of the criterion using these thresholds. Results: A peak time of 150 s and a WR of 30% were identified as optimal thresholds. As the criterion for malignancy, the combination of peak time ,150 s and WR ,30% provided a sensitivity of 79% (19/24), specificity of 95% (70/74) and an overall accuracy of 91% (89/98). Three of the five false-negative cases were malignant lymphomas of the parotid gland. Conclusion: Peak time ,150 s with WR ,30% comprised the optimal diagnostic criterion in predicting salivary gland malignancy, providing a sensitivity of 79% and specificity of 95%. The use of high temporal resolution might improve the accuracy of DCE-MRI. Advances in knowledge: Although several studies have reported the usefulness of DCE-MRI in the differential diagnosis of salivary gland tumours, the specific diagnostic criteria employed have differed widely. We determined the optimal criterion and its accuracy using a dynamic sequence with high temporal resolution.

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Section: Discussionmentioning

confidence: 99%

“…To obtain accurate TICs, a dynamic MRI sequence with high temporal resolution should be used. 6,16 However, the temporal resolution in most of the previous studies was relatively low (15-60 s), [8][9][10][11][12]14,[17][18][19][20] which may partly explain the inconsistencies between reports.…”

Section: The Authors Phong Dai Lam and Ami Kuribayashi Equally Contrimentioning

confidence: 99%

Differentiating benign and malignant salivary gland tumours: diagnostic criteria and the accuracy of dynamic contrast-enhanced MRI with high temporal resolution

Lam¹,

Kuribayashi²,

Imaizumi³

et al. 2015

BJR

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“…It has been reported that dynamic contrast-enhanced MRI (DCE-MRI) is useful for the differential diagnosis of some tumors, and many investigators have attempted to use it to identify differences between benign and malignant tumors, as well as to assess the malignancy of tumors [3][4][5][6]. We have also reported the usefulness of DCE-MRI for tumor diagnosis [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Application of dynamic contrast-enhanced MRI to differentiate malignant lymphoma from squamous cell carcinoma in the head and neck

et al. 2004

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Because malignant lymphoma, the second most common malignant tumor of the head and neck, and squamous cell carcinoma (SCC), the most common malignant tumor of the head and neck, require different treatments, it is important to be able to differentiate them. In the present study, we attempted to differentiate malignant lymphomas from SCCs using dynamic contrast-enhanced MRI (DCE-MRI). Seventeen lesions (in 8 cases) of malignant lymphoma and 30 cases of SCC were compared by DCE-MRI.Thirteen of 17 malignant lymphomas (76.5 %) showed the maximum contrast index (CI) at 90-180 s, while 26 of 30 SCCs (86.7%) showed the maximum CI at a much faster 60-105 s. There was a statistically significant difference between SCC and malignant lymphoma in the time needed reach the maximum CI (p=0.0177). There was also significant difference between SCC and malignant lymphoma in their maximum CIs (p<0.001), with the maximum CIs of 29/30 SCCs (96.7%) above 2.0, while 12/17 malignant lymphomas (70.6%) showed CIs of less than 2.0. We consider these findings to be useful for distinguishing lymphomas from SCCs.

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“…Extension of tumors from the deep lobe of a parotid gland is distinguishable from tumor arising anew in parapharyngeal space by a fine translucent line representing the compressed layer of fibroadipose tissue between the tumor and deep lobe of parotid [15]. MRI has been shown to be superior to computed tomography in the investigation of parapharyngeal space tumors [16,17]. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are the cornerstone in the initial evaluation.…”

Section: Discussionmentioning

confidence: 99%

Role of 18F-FDG PET Scan in Parapharyngeal Space Tumors: Report of a Rare Case and Review of the Literature

Oa¹,

Biyi²,

En-Nouali³

et al. 2017

J Cancer Sci Ther

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BackgroundParapharyngeal space (PPS) tumors are rare, accounting for 0.5% of all neoplasms of head and neck. PPS tumors may be primary, metastatic or a direct extension of tumors from the adjacent spaces. The frequency of benign and malignant tumors is about 80% and 20%, respectively. Most of them originate from the salivary gland (40-50%), followed by a neurogenic etiology and the remainder are a broad spectrum of miscellaneous tumors [1][2][3][4][5][6][7].The PPS is a lateral pharyngeal region. It is divided by muscular aponeurotic partition into an anterior (prestyloid) muscular compartment and a posterior (poststyloid) neurovascular compartment [1,[3][4][5][6][7]. Imaging is crucial for the assessment of PPS tumors. Surgery is performed based on information provided by these diagnostic modalities.This article will present a case of left parapharyngeal squamos cell carcinoma with unusual spinal metastases, and the potential role of FDG PET/CT will be illustrated. Case PresentationA 36-year-old male patient who showed up in April 2016 with 3 months' history of left side facial paralysis, left trismus, difficulty in swallowing and otological symptoms: otorrhea and otorrhagia. For the last month, he had developed a pharyngeal cavity mass. CT scan head and neck showed well defined heterogeneously enhancing left parapharyngeal solid mass (32×50×62 mm) with multiple area of necrosis, bulging into nasopharynx with extension to pharyngeal mucosal surface.The mass overwhelms the tympanic cavity and spreads to the ipsilateral external auditory meatus and pterygoid muscle. It causes the AbstractBackground: Tumors of the parapharyngeal space (PPS) are rare and account for only 0.5% of head and neck neoplasms. Approximately 80% of these tumors are benign lesions, yet they represent a formidable diagnostic and treatment challenge. They are difficult to diagnose because they have few symptoms, therefore, CT and MRI are essential to delineate the tumor extent, intracranial involvement and relationship to the adjacent vital structures.

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Parotid and parapharyngeal tumours: tissue characterization with dynamic magnetic resonance imaging

Cited by 54 publications

References 3 publications

Differentiating benign and malignant salivary gland tumours: diagnostic criteria and the accuracy of dynamic contrast-enhanced MRI with high temporal resolution

Differentiating benign and malignant salivary gland tumours: diagnostic criteria and the accuracy of dynamic contrast-enhanced MRI with high temporal resolution

Application of dynamic contrast-enhanced MRI to differentiate malignant lymphoma from squamous cell carcinoma in the head and neck

Role of 18F-FDG PET Scan in Parapharyngeal Space Tumors: Report of a Rare Case and Review of the Literature

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