Part 10: Special Circumstances of Resuscitation

Lavonas, Eric J.; Drennan, Ian R.; Gabrielli, A.; Heffner, Alan C.; Hoyte, Christopher; Orkin, Aaron; Sawyer, Kelly N.; Donnino, Michael W.

doi:10.1161/cir.0000000000000264

Cited by 243 publications

(135 citation statements)

References 176 publications

(177 reference statements)

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“…We also note that the American Heart Association updated their recommendation in October 2015 to include that empiric administration of IM or IN naloxone to all unresponsive opioid-associated life-threatening emergency patients may be reasonable as an adjunct to standard first aid and non-healthcare provider BLS protocols (Lavonas et al, 2015).…”

Section: *The Editor-in-chief and Senior Editors Of The Ijfae Particmentioning

confidence: 99%

When Should Naloxone Be Administered to the Undifferentiated Unresponsive Person?

Nemeth¹,

Bradley²

2018

IJFAE

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Section: *The Editor-in-chief and Senior Editors Of The Ijfae Particmentioning

confidence: 99%

When Should Naloxone Be Administered to the Undifferentiated Unresponsive Person?

Nemeth¹,

Bradley²

2018

IJFAE

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“…It is a safe, effective, short-acting opioid antagonist that acts to displace opioids from mu receptors. 9 Reversal of an overdose is possible within minutes, 10 and multiple delivery methods, including intramuscular and intranasal administration, are available. 3 The World Health Organization (WHO) strongly recommends the use of naloxone by bystanders in overdoses that occur in the community.…”

mentioning

confidence: 99%

Alberta’s provincial take-home naloxone program: A multi-sectoral and multi-jurisdictional response to overdose

Freeman

Bourque²,

Etches

et al. 2017

Can J Public Health

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SETTING: Alberta is a prairie province located in western Canada, with a population of approximately 4.3 million. In 2016, 363 Albertans died from apparent drug overdoses related to fentanyl, an opioid 50-100 times more toxic than morphine. This surpassed the number of deaths from motor vehicle collisions and homicides combined.INTERVENTION: Naloxone is a safe, effective, opioid antagonist that may quickly reverse an opioid overdose. In July 2015, a committee of communitybased harm reduction programs in Alberta implemented a geographically restricted take-home naloxone (THN) program. The successes and limitations of this program demonstrated the need for an expanded, multi-sectoral, multi-jurisdictional response. The provincial health authority, Alberta Health Services (AHS), used previously established incident command system processes to coordinate implementation of a provincial THN program.OUTCOMES: Alberta's provincial THN program was implemented on December 23, 2015. This collaborative program resulted in a coordinated response across jurisdictional levels with wide geographical reach. Between December 2015 and December 2016, 953 locations, including many community pharmacies, registered to dispense THN kits, 9572 kits were distributed, and 472 reversals were reported. The provincial supply of THN kits more than tripled from 3000 to 10 000. IMPLICATIONS:Alberta was uniquely poised to deliver a large, province-wide, multi-sectoral and multi-jurisdictional THN program as part of a comprehensive response to increasing opioid-related morbidity and mortality. The speed at which AHS was able to roll out the program was made possible by work done previously and the willingness of multiple jurisdictions to work together to build on and expand the program.KEY WORDS: Fentanyl; take-home naloxone; harm reduction; opioid overdose La traduction du résumé se trouve à la fin de l'article.

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“…Of these 5% of cases, 10% to 20% of patients present with cardiac arrest, with a mortality rate of 65-90% [3,4]. The guidelines of the European Society of Cardiology and the American Heart Association, on cardiopulmonary resuscitation, indicate the benefits of employing cardiopulmonary thrombolytic therapy if the patient is assumed to have a high-risk patient presenting with shock or cardiac arrest [1,5,6].…”

mentioning

confidence: 99%

“…In cases where the cause of cardiac arrest is PE, the use of thrombolysis and surgical or mechanical thrombectomy are considered reasonable treatment options [6]. However, it is difficult to correctly evaluate and select patients with PE as the one cause of cardiac arrest in real time [7].…”

mentioning

confidence: 99%

“…There is no consensus as to the criteria (risk factors, signs and symptoms) which constitute a high-risk PE candidate for thrombolysis [6]. Yet, it is suggested that ultrasonography can provide support for medical emergencies, as this has proven to be a critical tool with which to identify the reversible causes of circulatory collapse, allowing physicians to make decisions in real time [6].…”

mentioning

confidence: 99%

See 1 more Smart Citation

Ultrasonography on Detection of Massive Pulmonary Embolism as Cause of Cardiac Arrest

Carvajal¹,

Paz²,

Castaño³

2017

J Intensive Crit Care

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Part 10: Special Circumstances of Resuscitation

Cited by 243 publications

References 176 publications

When Should Naloxone Be Administered to the Undifferentiated Unresponsive Person?

When Should Naloxone Be Administered to the Undifferentiated Unresponsive Person?

Alberta’s provincial take-home naloxone program: A multi-sectoral and multi-jurisdictional response to overdose

Ultrasonography on Detection of Massive Pulmonary Embolism as Cause of Cardiac Arrest

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