Part II: Clinical Practice Guidelines for Adolescents and Young Adults With Down Syndrome: 12 to 21 Years

Cleve, Susan N. Van; Cannon, Sheila; Cohen, William I.

doi:10.1016/j.pedhc.2006.02.006

Cited by 62 publications

(33 citation statements)

References 10 publications

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“…Our results are generally in accordance with other studies [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] . However, our study differs from previously reported studies in two important respects.…”

Section: Discussionsupporting

confidence: 93%

“…The paediatricians were allowed to choose the "don't Around 1 in 767 babies are born with Down syndrome in Hong Kong [1] . A number of medical conditions occur more often among children with Down syndrome than among the general population [2][3][4][5] . These children need a wide range of services delivered by medical specialists, including paediatricians, general surgeons, orthopaedic surgeons, cardiothoracic surgeons, otolaryngologists and ophthalmologists.…”

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confidence: 99%

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Medical issues among children and teenagers with Down syndrome in Hong Kong

Yam¹,

Tse²,

Yu³

et al. 2008

Downs Syndr. Res. Pract.

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We examined the prevalence of medical problems in children and teenagers with Down syndrome in Hong Kong. Methods: Children with Down syndrome receiving care from seven regional hospitals were included and their hospital records were reviewed. A total of 407 patients, aged between 0.06 and 17.16 years were included. Cardiovascular problems were observed in 216 (53%), endocrine problems in 111 (27%), gastrointestinal problems in 46 (11%), haematological problems in 18 (4%), neurological problems in 27 (7%), sleep problems in 36 (9%), skeletal problems in 56 (14%), visual problems in 195 (48%) and auditory problems in 137 (34%). Conclusions: The prevalence of medical problems was high in children and teenagers with Down syndrome in Hong Kong and similar to previous findings elsewhere. Future studies on the local prevalence of medical problems in the adult population with Down syndrome would help to define their medical needs.ticipate. Children aged below 18 years old were included in the study. Demographic data collected included the name, sex, age, date of birth and identity card number. The age of a child was taken as the date on which the latest growth parameters were recorded. Children with the same name and identity card number were considered to be duplicate cases. For children without an identity card number submitted, they were regarded as duplicate cases if they had the same name, sex, age and date of birth. Hospital records were reviewed by participating paediatricians. Relevant data was recorded according to a pre-set questionnaire (SUPPLEMENTARY FIGURE 1). The questionnaire was designed by the participating paediatricians and epidemiologist who had special interests in Down syndrome. Nine major areas (including cardiovascular, endocrine, gastrointestinal, haematological, neurological, sleep, skeletal, visual and auditory) were studied. Each area was further classified and common conditions were listed. The paediatricians were asked to review the case records and to indicate whether the child had the condition. There was a column for "other problems" in each area so that unlisted conditions might be recorded. The paediatricians were allowed to choose the "don't Around 1 in 767 babies are born with Down syndrome in Hong Kong [1] . A number of medical conditions occur more often among children with Down syndrome than among the general population [2][3][4][5] . These children need a wide range of services delivered by medical specialists, including paediatricians, general surgeons, orthopaedic surgeons, cardiothoracic surgeons, otolaryngologists and ophthalmologists.Data on the prevalence of medical problems in these children is important for optimal service planning. Previous international and local studies have investigated many issues among children with Down syndrome, including: cardiovascular [6][7][8] , endocrinology [9][10][11][12] , neurology [13][14][15] , orthopaedics [16,17] , sleep [18] and visual and auditory [19][20][21][22][23] . This study aimed to examine the prevalence of various common m...

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Section: Discussionsupporting

confidence: 93%

mentioning

confidence: 99%

Medical issues among children and teenagers with Down syndrome in Hong Kong

Yam¹,

Tse²,

Yu³

et al. 2008

Downs Syndr. Res. Pract.

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“…Many of these children are mildly or asymptomatic. Current practice guidelines recommend screening at 2-3 years of age with TG autoantibodies with repeat screening in adolescence (65,66).…”

Section: Associated Conditions (Table 1)mentioning

confidence: 99%

Celiac Disease: Pathophysiology, Clinical Manifestations, and Associated Autoimmune Conditions

Barker

Liu

2008

Advances in Pediatrics

161

133

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“…Recommended laboratory tests are in the Table 1 . occurring before or during pregnancy can cause DS. It occurs in all races, social classes, and in all countries throughout the world (8,9) .…”

Section: Introductionmentioning

confidence: 99%

Recommendations on prenatal screening and the connections to other diseases such as thyroid dysfunction

Springer

Potluková²,

Límanová³

et al. 2012

Clinical Chemistry and Laboratory Medicine (CCLM)

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The aim of general maternal-foetal care is to ensure an uncomplicated birth of a healthy baby to a healthy mother. There is a large range of screening tests used during pregnancy: for gestational diabetes, infection, rhesus-D status, thyroid dysfunction, as well as other tests. An important part of prenatal care is the screening of major aneuploidies, primarily for Down ' s syndrome. This screening is possible in either the fi rst or second trimester, or in both. Management of this type of screening is very similar around the world. Hypothyroidism can affect the psychomotor development of the child. Thyroidstimulating hormone (TSH), autoantibodies against thyroperoxidase (TPOAb), and free thyroxin (FT4) were determined within our group of 7530 pregnant women. Elevated concentrations of TSH were found in 5.1 % , suppression was found in 2.9 % and 11.5 % were TPOAb positive. Either a familial or personal history of thyroid or autoimmune diseases was present in 58.3 % of those women who tested positive on any thyroid test. At minimum, 40 % of women TPOAb positive during pregnancy have some kind of thyroid disorders after delivery. These results support the effi cacy of general thyroid function screening in early pregnancy, as well as the follow-up after delivery of those women who are positive.

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Part II: Clinical Practice Guidelines for Adolescents and Young Adults With Down Syndrome: 12 to 21 Years

Cited by 62 publications

References 10 publications

Medical issues among children and teenagers with Down syndrome in Hong Kong

Medical issues among children and teenagers with Down syndrome in Hong Kong

Celiac Disease: Pathophysiology, Clinical Manifestations, and Associated Autoimmune Conditions

Recommendations on prenatal screening and the connections to other diseases such as thyroid dysfunction

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