2014
DOI: 10.1177/1352458514526943
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Partial acute transverse myelitis is a predictor of multiple sclerosis in children

Abstract: Acute partial transverse myelitis and brain MRI abnormalities at initial presentation are significantly predictive of a subsequent diagnosis of MS in children with ATM. These findings suggest that closer brain MRI monitoring after acute partial transverse myelitis might make the earlier introduction of disease-modifying therapies possible.

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Cited by 13 publications
(16 citation statements)
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“…[6][7][8][9][10][11][12] A bimodal age distribution is observed in children under 5 and older than 10 years of age. 3,8,9,[11][12][13] There is no difference in ethnicity prevalence. A range of prodromal infections are reported in the preceding 30 days in up to 66% of ATM cases.…”
mentioning
confidence: 97%
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“…[6][7][8][9][10][11][12] A bimodal age distribution is observed in children under 5 and older than 10 years of age. 3,8,9,[11][12][13] There is no difference in ethnicity prevalence. A range of prodromal infections are reported in the preceding 30 days in up to 66% of ATM cases.…”
mentioning
confidence: 97%
“…3,8 New MRI sequences (e.g., double inversion recovery, phase sensitive inversion recovery) may detect cord lesions. 23 Although repeat spinal cord imaging after 5-7 days may reveal spinal cord atrophy, 12,13 other novel techniques used in adult MS studies, such as magnetization transfer ratio and diffusion tensor imaging, may help to quantify and correlate with disability earlier in the disease. 24 These novel techniques may be challenging in young children because they involve increased imaging time and associated sedation.…”
Section: Differential Diagnosis and Evaluationmentioning
confidence: 99%
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