Partial characterization of green synthesized silver nanoparticles of Cardiospermum halicacabum and Butea monosperma aqueous extract combination (CHBMCSNP)

Rameshwari, K. Sudha; Abirami, M.; Christobel, R Gloria Jemmi

doi:10.5958/0974-360x.2020.01084.7

Cited by 4 publications

(2 citation statements)

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“…The FTIR analysis provided complete clarity regarding the functional groups of the extract. Because of these functional groups, the results from various plant extracts displaying substantial medicinal value were consistent with the medium peak values at 1574 cm -1 and 1394 cm -1 , indicating aromatic substances and more alcohol involvement, as well as the intense, broad peak at 3231 cm -1 , indicative of alcohol OH stretching [24]. The important bands at 1249 and 1011 cm -1 confirmed the presence of C-O stretching and substituted aromatic compounds, respectively.…”

Section: Discussionsupporting

confidence: 63%

Comparative In Vitro and In Silico Analyses of Phytochemicals From Butea monosperma for Wound-Healing Potential in Human Cells

Sudhakar Rao,

Ryntathiang,

Behera

et al. 2024

Cureus

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Aim The objective of this study is to investigate the phytochemicals present in Butea monosperma and assess their potential for healing wounds using a computational comparative method. Materials and methods The phytochemical substances derived from B. monosperma were examined using a phytochemical test, Fourier-transform infrared (FTIR) spectroscopy, and gas chromatography-mass spectroscopy (GCMS). The chemical structures of these substances were investigated in silico using computational techniques to predict their wound-healing capacity. The molecular docking tests evaluate the binding strengths of the phytochemicals to specific proteins that play a major role in wound-healing mechanisms. The pharmacokinetic features of the substances were evaluated by analyzing their ADMET (absorption, distribution, metabolism, excretion, and toxicity) profiles. Results The computer analysis found several phytochemicals from B. monosperma that bind strongly to the proteins for wound healing: compounds such as hexanoic acid, 2,7-dimethyloct-7-en-5-yn-4-yl ester, 1,3,5-pentanetriol, 3-methyl-, and 2-butyne-1,4-diol. The ADMET analysis indicated favorable pharmacokinetic properties for the majority of the identified compounds, with low predicted toxicity. Conclusion Based on the in silico analysis, the phytochemicals in B. monosperma possess significant potential for use in wound-healing applications. These findings required additional in vitro and in vivo studies to confirm the effectiveness and safety of these drugs for improving wound healing. This study emphasizes the potential of B. monosperma as a source of innovative medicinal substances for wound care.

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Section: Discussionsupporting

confidence: 63%

Comparative In Vitro and In Silico Analyses of Phytochemicals From Butea monosperma for Wound-Healing Potential in Human Cells

Sudhakar Rao,

Ryntathiang,

Behera

et al. 2024

Cureus

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“…Aqueous extract of C. halicacabum and B.monosperma leaves appeared to show the presence of most phytoconstituents compared to ethanol extract and methanol extract. The aqueous extract is one of the best extracts followed by ethanol extract (Rameshwari et al 2020). Phytochemical screening reveals that the C.halicacabum extract contains glycosides, carbohydrates, flavonoids, phytosterols, phenolic compounds and saponin (Zalke et al 2013).…”

Section: Discussionmentioning

confidence: 99%

Comparative Study on Phytochemical Screening of Root and Bark with Leaf of Cardiospermum Halicacabum

Priya¹,

Rani²

2021

alinteri

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Aim: The Present study was designed to compare the phytochemical screening of root and bark with leaf of Cardiospermum halicacabum. Materials and Methods: Samples were taken leaf (N=24) root and bark (N=24) based on the total sample size using clinical.com. The leaf, root and bark extract were collected. The phytochemicals were extracted by sequential extraction using three solvents methanol, ethanol and acetone. The quantification of flavonoids and phenols was performed by using Folin-Ciocalteu and quercetin as standard. Quantification of tannins was determined by using an insoluble polyvinyl-polypyrrolidone (PVPP) as standard. Results: Statistical analysis showed that methanol extract of root (0.49mg/ml) has highest phenolic content and acetone extract of root has highest tannin (0.64mg/ml) and flavonoid (1.18mg/ml) content when compared with leaf and bark. There appears to be a statistically significant difference in the mean of root when compared with leaf and bark (p<0.01, independent samples). Conclusion: In this study root appears to have better phytochemical and phenol content when compared with the content in leaf and bark.

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Ecofriendly bio-synthesis and spectral characterization of copper nanoparticles using fruit extract of Pedalium murex L.: in vitro evaluation of antimicrobial, antioxidant and anticancer activities on human lung cancer A549 cell line

Kannan,

Jaisankar,

Rajendran

et al. 2023

Materials Technology

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Partial characterization of green synthesized silver nanoparticles of Cardiospermum halicacabum and Butea monosperma aqueous extract combination (CHBMCSNP)

Cited by 4 publications

References 0 publications

Comparative In Vitro and In Silico Analyses of Phytochemicals From Butea monosperma for Wound-Healing Potential in Human Cells

Comparative In Vitro and In Silico Analyses of Phytochemicals From Butea monosperma for Wound-Healing Potential in Human Cells

Comparative Study on Phytochemical Screening of Root and Bark with Leaf of Cardiospermum Halicacabum

Ecofriendly bio-synthesis and spectral characterization of copper nanoparticles using fruit extract of Pedalium murex L.: in vitro evaluation of antimicrobial, antioxidant and anticancer activities on human lung cancer A549 cell line

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