Partial Characterization of the in Vivo Metabolites of DDT-C14 in Triatoma infestans1

Acosin, M.; Morello, Antonio; Scaramelli, N.

doi:10.1093/jee/57.6.974

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Metabolism Of Bridged Diphenyl Acaricides1

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1968

1985

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Cited by 19 publications

(3 citation statements)

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“…14C-ring-labeled DDT was obtained from the Radiochemical Centre, Amersham. DDT was chromatographically purified as described previously (Agosin et al, 1964). Puromycin dihydrochloride was purchased from Mann Research Biochemicals; spermine from Nutritional Biochemicals Co.…”

Section: Methodsmentioning

confidence: 99%

Protein synthesis in polymers from houseflies and the effect of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane

Litvak¹,

Agosín²

1968

Biochemistry

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Section: Methodsmentioning

confidence: 99%

Protein synthesis in polymers from houseflies and the effect of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane

Litvak¹,

Agosín²

1968

Biochemistry

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“…In investigations on the fate of DDT in Triatoma infestans, Agosin and coworkers found that DDT was metabolized to DDE, dicofol, and a third chlorform-soluble metabolite (47). Dicofol was also metabolized to this same metabolite which co-chromatographed with dipchlorobenzhydrol (DBH).…”

Section: Metabolism Of Bridged Diphenyl Acaricidesmentioning

confidence: 99%

Properties and Actions of Bridged Diphenyl Acaricides

March¹

1976

Environmental Health Perspectives

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The properties and actions of the bridged diphenyl acaricides are discussed. These pesticides, which are more or less structurally related to DDT, were the first of the specific acaricides to be developed. They exhibit remarkable properties of specificity, being primarily toxic to phytophagous mites but of very low toxicity to most nontarget species, including insects, fish, birds, and mammals. Although many important facets of their broad mode of action are understood, virtually nothing is known of their primary mode of action or the underlying bases of their specificities. In most ways they are model compounds for integrated control and pest management activities and thus merit greater attention than they have received to elucidate the fundamentals underlying their unusual properties and actions.

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“…Metabolic hydroxylation of the aromatic rings of the para,para' isomers of DDT-type compounds (DDT, DDD, DDE, etc.) have not been conclusively described previously, although the possible formation of phenolic metabolites of , '-DDT (l,l,l-trichloro-2,2'-bis(4-chlorophenyl)ethane) has been indicated in severed reports (e.g., Jensen et al, 1957;Dinamarca et al, 1962;Agosin et al, 1964;Morello, 1965;Sanchez, 1966;Schuntner and Schnitzerling, 1966;Oppenoorth and Houx, 1968; Welch et al, 1969; Agosin et al, 1969).…”

mentioning

confidence: 99%

Metabolic hydroxylation of the aromatic rings of 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (p,p'-DDE) by the rat

Sundström¹

1977

J. Agric. Food Chem.

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Partial Characterization of the in Vivo Metabolites of DDT-C14 in Triatoma infestans1

Cited by 19 publications

References 0 publications

Protein synthesis in polymers from houseflies and the effect of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane

Protein synthesis in polymers from houseflies and the effect of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane

Properties and Actions of Bridged Diphenyl Acaricides

Metabolic hydroxylation of the aromatic rings of 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (p,p'-DDE) by the rat

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