Partial recovery of SARS-CoV-2 immunity after booster vaccination in renal transplant recipients

Considerations on COVID-19 vaccination

“…This aspect also implies that the effects of COVID-19 vaccination need to take into account the population of subjects involved. For example, patients on dialysis had effective cellular and humoral immunity that was comparable to that observed in healthy individuals after the first two-dose immunization with COVID-19 vaccine, displaying 100% seroconversion and cellular immunity in 87% cases after booster vaccination [7] . However, in renal transplant recipients, more than 50% of patients had no cellular and/or humoral immunity after the first two-dose immunization and, after booster, 20% patients still did not have detectable antibodies and 37.5% lacked cellular immunity to SARS-CoV-2 [7] .…”