1974
DOI: 10.1056/nejm197408152910703
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Partial Reduction of Blood Pressure and Prevention of Complications in Hypertension

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Cited by 95 publications
(16 citation statements)
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“…In fact, it is clear that lesser reductions, particularly in moderate to severe hypertension, have a protective effect. 10 Nonetheless, the weight of evidence supports the position that the lower the BP achieved through treatment, the fewer the complications of hypertension.…”
Section: Relationship Of Bp Control To Morbidity and Mortalitymentioning
confidence: 99%
“…In fact, it is clear that lesser reductions, particularly in moderate to severe hypertension, have a protective effect. 10 Nonetheless, the weight of evidence supports the position that the lower the BP achieved through treatment, the fewer the complications of hypertension.…”
Section: Relationship Of Bp Control To Morbidity and Mortalitymentioning
confidence: 99%
“…While any reduction is worth while (Hamilton et al, 1964;Veterans Administration Co-Operative Study Group, 1967, prognosis is likely to be better if the diastolic blood pressure is maintained below 100 mmHg (Beevers et al, 1973;Taguchi and Freis, 1974).…”
Section: Discussionmentioning
confidence: 99%
“…17 Subsequent trials comparing treatment versus placebo (or routine care) in patients with moderate, then mild, diastolic hypertension demonstrated incontrovertibly that reduction of elevated blood pressure reduced stroke incidence. 18,19 These trials focused on diastolic hypertension in persons Ͻ65 years old. In more recent trials, reduction of systolic pressure in elderly persons with isolated systolic hypertension consistently prevented stroke, and the benefit far exceeded the risk.…”
Section: Prevention Of Stroke By Risk Factor Modificationmentioning
confidence: 99%