Partial splenic embolization for the treatment of chronic idiopathic thrombocytopenic purpura.

Miyazaki, Masaru; Itoh, Hiroshi; Kaiho, Tatsuo; Ohtawa, Satoshi; Ambiru, Satoshi; Hayashi, Satoru; Nakajima, Nobuko; Oh, Hakumei; Asai, Takayoshi; Iseki, Toshiyuki

doi:10.2214/ajr.163.1.8010197

Cited by 59 publications

(35 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mozes et al [7] described the benefit of partial splenic embolization (PSE) in reducing the prevalence of complications from splenic artery embolization. Miyazaki et al [8] reported the effectiveness of PSE in thrombocytopenia. Their reports suggested that PSE might be a safe and effective alternative to splenectomy in the treatment of thrombocytopenia.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the effect of partial splenic embolization on platelet values for liver cirrhosis patients with thrombocytopenia

Lee

Leung

Wang

et al. 2007

WJG

View full text Add to dashboard Cite

AIM:To investigate the effect of partial splenic embolization (PSE) on platelet values in liver cirrhosis patients with thrombocytopenia and to determine the effective embolization area for platelet values improvement. METHODS:Blood parameters and liver function indicators were measured on 10 liver cirrhosis patients (6 in Child-Pugh grade A and 4 in grade B) with thrombocytopenia (platelet values < 80 × 10 3 /μL) before embolization. Computed tomography scan was also needed in advance to acquire the splenic baseline. After 2 to 3 d, angiography and splenic embolization were performed. A second computed tomography scan was made to confirm the embolization area after 2 to 3 wk of embolization. The blood parameters of patients were also examined biweekly during the 1 year follow-up period. RESULTS:According to the computed tomography images after partial splenic embolization, we divided all patients into two groups: low (< 30%), and high (≥ 30%) embolization area groups. The platelet values were increased by 3 times compared to baseline levels after 2 wk of embolization in high embolization area group. In addition, there were significant differences in platelet values between low and high embolization area groups. GPT values decreased significantly in all patients after 2 wk of embolization. The improvement in platelet and GPT values still persisted until 1 year after PSE. In addition, 3 of 4 (75%) Child-Pugh grade B patients progressed to grade A after 2 mo of PSE. The complication rate in < 30% and ≥ 30% embolization area groups was 50% and 100%, respectively.

show abstract

Section: Introductionmentioning

confidence: 99%

Evaluation of the effect of partial splenic embolization on platelet values for liver cirrhosis patients with thrombocytopenia

Lee

Leung

Wang

et al. 2007

WJG

View full text Add to dashboard Cite

show abstract

“…The effects of PSE in some cases are temporary, necessitating a repeat procedure. With careful attention to a few technical principles, the incidence of complications after PSE has declined [10,11,14,16,17,20,22]. These principles, referred to as the Spigos technique, include (1) aseptic technique, (2) antibiotic coverage, (3) avoidance of excessive infarction of splenic mass (<60-70%), and (4) effective postembolization analgesia [15].…”

mentioning

confidence: 99%

Splenic artery embolization before laparoscopic splenectomy An update

1998

View full text Add to dashboard Cite

Preoperative splenic artery embolization is not necessary for spleens shorter than 20 cm. Increased experience and mostly the lateral surgical approach have permitted a shorter operation and a low conversion rate (4%) similar to the rate achieved with embolization and the anterior approach in the initial stages of the study. Embolization is used for 20- to 30-cm spleens. The conversion rate is higher (17%), and blood replacement is required frequently (83%). Despite embolization, laparoscopic splenectomy for spleens longer than 30 cm is futile at this time (100% conversion).

show abstract

“…Splenic artery embolization was first described in the 1970s and has since been used in different clinical settings, including traumatic spleen rupture, portal hypertension-related ascites, immune thrombocytopenic purpura, hemoglobinopathies, and hereditary spherocytosis [1][2][3][4][5]. Use of splenic embolization in patients with autoimmune hemolytic anemia is rarely reported [6].…”

Section: Discussionmentioning

confidence: 99%

Splenic artery embolization: An alternative approach in a critically ill patient with autoimmune hemolytic anemia

Tanrıöver

Peynircioğlu²,

Ergan

et al. 2011

Turk J Hematol

View full text Add to dashboard Cite

Assessment of general health status and hematological parameters usually precedes the use of invasive diagnostic and therapeutic procedures in critically ill patients. Angiography can be effective and safe as a substitute for major surgical procedures, or as a bridging therapy in such cases. We present a critically ill patient with hemolytic anemia that underwent splenic artery embolization as a bridging therapy. We aimed to emphasize that minimally invasive approaches and multidisciplinary care can be utilized in the treatment of critically ill patients with accompanying hematological disease. (Turk J Hematol 2011; 28: 135-8) Key words: Critical care medicine, therapeutic embolization, hemolytic anemia ÖzetKritik derecede ağır bir hastanın genel durum bozukluğu ve hematolojik parametreleri, invazif tanı ve tedavi girişimlerinin uygulanmasına izin vermeyebilir. Bu tür olgularda, anjiyografik yaklaşımlar büyük cerrahi girişimlerin yerini tutacak veya köprü tedavisi görevi görecek güvenilir ve etkili bir tedavi yöntemi olabilir. Burada, köprü tedavisi olarak dalak arteri embolizasyonu yapılan hemolitik anemili kritik durumda ağır bir hasta sunulmaktadır. Bu olgu, ciddi bir kan hastalığının eşlik ettiği bu tür hastalarda multidisipliner bakımın önemini ve daha az invazif yaklaşımların seçilmesinin uygun olabileceğini vurgulamaktadır. (Turk J Hematol 2011; 28: 135-8)

show abstract

Partial splenic embolization for the treatment of chronic idiopathic thrombocytopenic purpura.

Cited by 59 publications

References 12 publications

Evaluation of the effect of partial splenic embolization on platelet values for liver cirrhosis patients with thrombocytopenia

Evaluation of the effect of partial splenic embolization on platelet values for liver cirrhosis patients with thrombocytopenia

Splenic artery embolization before laparoscopic splenectomy An update

Splenic artery embolization: An alternative approach in a critically ill patient with autoimmune hemolytic anemia

Contact Info

Product

Resources

About