Partial Spontaneous Regression of Bowen's Disease

Corona of Glomerular Vessels: A Diagnostic Marker of Hyperkeratotic Bowen's Disease

“…In 1996, Murata and colleagues compared the histopathology of lesional, interlesional, and perilesional skin from 17 patients with irregularly shaped Bowen's disease lesions for evaluation of histopathologic evidence of regression. The lesional and interlesional skin demonstrated vascularity, amyloid deposition, melanophages, inflammatory cell infiltrates, and dermal fibrosis, but the perilesional skin showed no such findings . The pathoetiology of blood vessel proliferation outside the lesion is not clear.…”

Comparison of cryotherapy with curettage in the treatment of Bowen’s disease: a prospective study

“…However, spontaneous regression has also been observed. 6 It is therefore debatable as to how aggressively BD should be treated. Some patients prefer not to have any treatment, and in certain circumstances this may be most appropriate.…”

Spontaneous complete regression of multiple Bowen's disease in the web‐spaces of the feet

“…The present case demonstrates the complete regression of multiple Bowen's disease lesions occurring in the web‐spaces of the patient's feet without any treatment. Several cases of spontaneous partial regression of Bowen's disease have been reported; 1,2 however, only one case of spontaneous complete regression of Bowen's disease has been reported in the English literature, when Fas‐mediated apoptosis was involved 3 . In our case, the HPV type 16‐related genome was identified in the primary lesions of Bowen's disease by ISH.…”