Partial status epilepticus causing a transient left ventricular apical ballooning

Abstract

Transient left ventricular apical ballooning also called Takotsubo cardiomyopathy is a recently described cardiac syndrome. It often affects postmenopausal women having an acute physical or emotional stress, but it have also been described after convulsive status epilepticus. Although this association is rare and left ventricular function often recovers, it would be useful to the neurologist to be aware of the signs leading to this diagnosis, to improve the cardiac later care. Here we report a patient with partial status epilepticus in whom the diagnosis of transient left ventricular apical ballooning was made. We describe the diagnostic criteria and the potential complications that should be monitored.

Prevalence and Risk Factors of Stress Cardiomyopathy After Convulsive Status Epilepticus in ICU Patients

“…Although SC is commonly described in various clinical circumstances, its relation with CSE has been rarely reported (10)(11)(12)(13)(14)(15)(16). As far as we know, this is the first prospective study monitoring hemodynamics and cardiac function during the acute management of CSE in the ICU.…”

“…Subsequently, several case reports suggested that epilepsy or CSE could result in SC (10)(11)(12)(13)(14)(15)(16). Nevertheless, the frequency of SC in patients with CSE remains currently unknown and may be underestimated (17).…”

Recurrence of Postoperative Stress-Induced Cardiomyopathy Resulting from Status Epilepticus

“…Current subtypes recognized are apical and nonapical regional wall dysfunction, which in some instances may be associated with a subset of precipitating stressors. Recent case studies have involved patients with nonapical ballooning cardiomyopathy following hemorrhagic stroke or seizures in particular [ 5 , 9 , 10 ]. The case presented here involves recurrence of nonapical stress-induced cardiomyopathy following status epilepticus.…”

Epilepsy and Takotsubo Cardiomyopathy: A Case Report

“…In an animal model, neurogenic cardiac damage occurred in mice with adrenalectomy to reduce circulating catecholamines, although this damage was attenuated compared to that of non-adrenalectomized mice (18). In the clinical setting, partial status epilepticus that originated in the temporal lobe, not a generalized seizure, was related to takotsubo cardiomyopathy (19). These results might suggest that not only catecholamine release because of the stress from the generalized epileptic seizure but also stimulation of the central nervous system including the temporal region might cause takotsubo cardiomyopathy.…”