Partial unilateral third nerve palsy and bilateral internuclear ophthalmoplegia: An unusual presentation of multiple sclerosis

Gnanaraj, Lawrence; Rao, Veena

doi:10.1038/eye.2000.171

Cited by 9 publications

(1 citation statement)

References 3 publications

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“…An isolated CN III palsy as the presenting sign of MS is very unusual [151][152][153]. Painful pupil-involving [154] and pupil-sparing [152] CN III palsies have been reported in association with MS. Other unusual patterns, such as bilateral pupil-sparing CN III palsy [121], unilateral partial CN III palsy with bilateral INO [155] and an inferior rectus palsy associated with a nuclear CN III lesion [153] have been documented in patients with MS.…”

Section: Cn III Palsymentioning

confidence: 95%

The Neuro-Ophthalmology of Multiple Sclerosis

2012

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Multiple sclerosis (MS) is a disease marked by focal demyelinating inflammatory plaques throughout the CNS. Neuro-ophthalmologic sequelae are common in MS and may arise from the disease itself or from treatment of the disease. Both afferent and efferent functions may be affected. Despite much progress, our understanding of the pathophysiology of MS, and the efficacy of our available treatments, remain inadequate. Here, we review the chief neuro-ophthalmologic abnormalities associated with MS and discuss the emerging diagnostic and therapeutic advances that are likely to further our understanding of MS and its treatment.

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