2022
DOI: 10.1016/j.ejim.2022.06.018
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Participants’ informed consent in adaptive, platform drug trials in hospitalized COVID-19 patients: Not all approaches are ethically acceptable

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Cited by 6 publications
(2 citation statements)
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“…However, even during a pandemic that threatens the health of many people such as the COVID-19 pandemic, the IC process must not be abandoned as it is one of the most important pillars of research ethics [ 20 ]. Alternative methods to obtain IC must be critically reviewed for their suitability, as they may prove to be ethically questionable [ 21 ]. It might be helpful to combine several methods of obtaining IC [ 5 , 20 , 22 ].…”
Section: Discussionmentioning
confidence: 99%
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“…However, even during a pandemic that threatens the health of many people such as the COVID-19 pandemic, the IC process must not be abandoned as it is one of the most important pillars of research ethics [ 20 ]. Alternative methods to obtain IC must be critically reviewed for their suitability, as they may prove to be ethically questionable [ 21 ]. It might be helpful to combine several methods of obtaining IC [ 5 , 20 , 22 ].…”
Section: Discussionmentioning
confidence: 99%
“…However, deciding on the degree of risk and, hence, whether a study qualifies for a waiver is extremely difficult during a pandemic. In this regard, the handling of IC in some studies conducted with COVID-19 patients was ethically unacceptable [ 21 , 28 ]. It should not go unmentioned that, in addition to ethical concerns, there are also clear legal requirements in Germany.…”
Section: Discussionmentioning
confidence: 99%