Participation After Multidisciplinary Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults: A Systematic Review

Brasure, Michelle; Lamberty, Greg J.; Sayer, Nina A.; Nelson, Nathaniel W.; MacDonald, Roderick; Ouellette, Jeannine; Wilt, Timothy J

doi:10.1016/j.apmr.2012.12.019

Cited by 82 publications

(74 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite the potential value of longer-term and multidisciplinary rehabilitation in helping to maximize physical, cognitive and psychological outcomes following ABI, evidence relating to treatment outcome and efficacy is limited in quantity [6][7][8][9][10]. This is partly due to the complexity of conducting research with a heterogeneous population encompassing different neurological conditions (i.e.…”

Section: Introductionmentioning

confidence: 95%

Functional outcomes of community-based brain injury rehabilitation clients

et al. 2014

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 95%

Functional outcomes of community-based brain injury rehabilitation clients

et al. 2014

View full text Add to dashboard Cite

show abstract

“…These impairments may in turn lead to changes in identity (Muenchberger, Kendall, and Neal, 2008) and limitations in activities and social participation (Brasure et al, 2013;Lu et al, 2012). Physiotherapy for people with sTBI is guided by current evidence relating to neuroplasticity (Brodal, 2010), motor learning (Shumway-Cook and Wollacott 2012), and variants of physiotherapy (e.g.…”

Section: Introductionmentioning

confidence: 99%

Embodiment and self in reorientation to everyday life following severe traumatic brain injury

Sivertsen

Normann

2014

Physiotherapy Theory and Practice

View full text Add to dashboard Cite

People with severe traumatic brain injury (sTBI) are often young and need long-term follow-up as many suffer complex motor, sensory, perceptual and cognitive impairments. This paper aims to introduce phenomenological notions of embodiment and self as a framework to help understand how people with sTBI experience reorientation to everyday life, and to inform clinical practice in neurological physiotherapy. The impairments caused by the sTBI may lead to a sense of alienation of one's own body and changes in operative intentionality and in turn disrupt the reorganization of self, identity, everyday life and integration/co-construction of meaning with others. Applying a first-person conception of the body may extend insights into the importance of an adapted and individualized approach to strengthen the sensory, perceptual and motor body functions, which underpin the pre-reflective and reflective aspects of the self. It seems important to integrate these aspects, while also paying attention to optimizing co-construction of meaning for the person with sTBI in the treatment context. This requires understanding the patient as an experiencing and expressive body, a lived body (body-as-subject) and not just the body-as-object as is favored in more traditional frameworks of physiotherapy.

show abstract

“…Severe TBI patients are mostly subjected to surgery (acute treatment) to remove or repair ruptured blood vessels and bruised brain tissue, as well as other complications due to brain trauma, or prescribed with medications to mitigate symptoms such as headaches, chronic pain, behavioral problems, depression, and seizures (13,120,121). A majority of TBI patients are relegated to rehabilitation therapy (14,33,59,117), although obviously this type of intervention does not prevent or reverse much of the brain damage resulting from the injury. Indeed, there is a substantial need for clinically efficacious therapies for TBI, especially those that prevent and/or reduce secondary injury and facilitate long-term functional recovery after TBI.…”

Section: Traumatic Brain Injury (Tbi)mentioning

confidence: 99%

G-CSF as an Adjunctive Therapy with Umbilical Cord Blood Cell Transplantation for Traumatic Brain Injury

et al. 2015

View full text Add to dashboard Cite

Traumatic brain injury (TBI), a major contributor to deaths and permanent disability worldwide, has been recently described as a progressive cell death process rather than an acute event. TBI pathophysiology is complicated and can be distinguished by the initial primary injury and the subsequent secondary injury that ensues days after the trauma. Therapeutic opportunities for TBI remain very limited with patients subjected to surgery or rehabilitation therapy. The efficacy of stem cell-based interventions, as well as neuroprotective agents in other neurological disorders of which pathologies overlap with TBI, indicates their potential as alternative TBI treatments. Furthermore, their therapeutic limitations may be augmented when combination therapy is pursued instead of using a single agent. Indeed, we demonstrated remarkable combined efficacy of human umbilical cord blood (hUCB) cell therapy and granulocyte-colony-stimulating factor (G-CSF) treatment in TBI models, providing essential evidence for the translation of this approach to treat TBI. Further studies are warranted to determine the mechanisms underlying therapeutic benefits exerted by hUCB + G-CSF in order to enhance its safety and efficacy in the clinic.

show abstract

Participation After Multidisciplinary Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults: A Systematic Review

Cited by 82 publications

References 32 publications

Functional outcomes of community-based brain injury rehabilitation clients

Functional outcomes of community-based brain injury rehabilitation clients

Embodiment and self in reorientation to everyday life following severe traumatic brain injury

G-CSF as an Adjunctive Therapy with Umbilical Cord Blood Cell Transplantation for Traumatic Brain Injury

Contact Info

Product

Resources

About