Participation in research improves overall patient management: insights from the Global Rheumatic Heart Disease registry (REMEDY)

Prendergast, E A; Perkins, Susan; Engel, Mark E; Cupido, Blanche; Francis, Veronica; Joachim, Alexia; Kebsi, M Al; Bode‐Thomas, Fidelia; Damasceno, Albertino; Fadl, Azza Abul; Sayed, Amer; Gitura, Bernard; Ibrahim, Ahmed S.; Mucumbitsi, Joseph; Adeoye, Abiodun M.; Musuku, John; Okello, Emmy; Olunuga, Taiwo; Sheta, Sahar; Mayosi, Bongani M.; Zühlke, Liesl; investigators, Remedy

doi:10.5830/cvja-2017-054

Cited by 10 publications

(5 citation statements)

References 11 publications

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“…The present finding was also consistent with other studies conducted in Africa: Uganda, 56,57 Malawi 58 , Tanzania, 59 and South Africa. 60 In this study, the commonest reasons reported for missing monthly benzathine prophylaxis injections was long distance from hospitals (56.9%), lack of money (38%), unaffordability (30.8%), and inconvenient work schedule (22.5%). This finding is also supported by different studies.…”

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confidence: 65%

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<p>Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study</p>

Adem¹,

Gemechu²,

Jarso³

et al. 2020

PPA

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Background: Rheumatic heart disease (RHD) is a major cause of preventable premature cardiovascular-related death in developing countries. However, information regarding adherence rates and associated factors is limited and inconsistent in Ethiopia. Methods: A cross-sectional study was conducted from August to November 2019 among selected RHD patients on follow-up at four hospitals in Jimma zone. Data were collected using a structured questionnaire. Adherence of RHD patients to secondary prophylaxis in the previous consecutive 12 months was assessed based on the annual frequency of received prophylaxis (monthly injection of benzathine penicillin). Good adherence was considered the patient receiving >80% of the annual dose. The collected data were entered into Epidata 3.1 and analysed using SPSS 23. Results: A total of 253 RHD patients taking prophylaxis were included in the analysis, and of those 178 (70.4%) were female, giving a male:female ratio of 1:2.4. The mean age was 24 ±11 (6-65) years. About 63% had good adherence to benzathine penicillin prophylaxis. New York Heart Association functional class I and II, rural residence, >30 km from health facility, and duration of prophylaxis >5 years were associated with poor adherence (respectively: AOR 12.6 [95% CI 2.5-63], P=0.

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confidence: 65%

“…The present finding was also consistent with other studies conducted in Africa: Uganda, 56 , 57 Malawi 58 , Tanzania, 59 and South Africa. 60 …”

Section: Discussionmentioning

confidence: 99%

<p>Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study</p>

Adem¹,

Gemechu²,

Jarso³

et al. 2020

PPA

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“…Indeed, the experience of research team members from UEM teaching hospital that was the core part of our program was evaluated through an online survey complemented with telephone interviews to gather additional qualitative data, demonstrating that participation in clinical research has a positive impact on patient management. 49 Furthermore, we have developed sustainable strategies and a network of national and international academic institutions working together on multiple common goals (UniLúrio, UEM, UPM, UniZambeze, UCSD, UNL-IHMT, Oporto University, Universidad de Granada, Universidade do Aveiro, Universidade Técnica de Lisboa, Universidade Federal de Minas Gerais). We have followed other initiatives which were successful such as the Better Health Information for Better Health Policy (INDEPTH) network, Consortium for Health Systems Policy Analysis in Africa (CHEPSAA), the partnership between Makerere University and Karolinska Institutet, the African/Asian Regional Capacity Development and RAHI-SATHI Indo-US are underway elsewhere.…”

Section: Discussionmentioning

confidence: 99%

Design and Implementation of Postgraduate Programs in Health in a Resource-Limited Setting in Mozambique (The Lúrio University)

Noormahomed¹,

Mandane²,

Cuambe³

et al. 2021

AMEP

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Purpose: To describe the strategies used to design and implement three postgraduate programs at Lúrio University (UniLúrio), a resource-limited setting, in northern Mozambique. Methods: We conducted a longitudinal, descriptive case study from 2011 to 2018 in two phases: 1) needs assessment (2011)(2012), 2) implementation strategies (2013)(2014)(2015)(2016)(2017)(2018), taking into account innovations whenever necessary. Results: Several obstacles and barriers to the establishment of postgraduate programs were identified. These included a lack of a core curricula aimed at postgraduate programs, shortage of human resources for teaching and mentorship, limited teaching and research infrastructures, limited financial resources, and lack of administrative capacity. With the support of the Medical Education Partnership Initiative (MEPI), three Master degree programs were designed and implemented. During the period of 2013-2018, UniLúrio enrolled 202 students, distributed as follows: Master degree in Tropical Medicine and Global Health (55), Master degree in Health Professional Education (99), and Master degree in Nutrition and Food Security (48). Of those, 152 (75.2%) obtained a Postgraduate Diploma as they did not present a master dissertation, 89 (44.0%) obtained their Master degree, 30 (14.8%) dropped out, and 20 (9.9%) are awaiting decision. UniLurio's staff trained a Master's degree or a Postgraduate Diploma in 34 (16.8%) and 15 (7.4%), respectively. Our strategies allowed us to improve research capacity building, and set the basis for long-term sustainability by allowing for the establishment of other postgraduate programs, and offered UniLurio a strong role in its internationalization. Conclusion: By sharing multiple resources, long-lasting partnerships were established with multiple institutions, and competency-based training and postgraduate studies management were developed. Research and eLearning were leveraged, retention and faculty development was enhanced, and some inequalities within the country were reduced. These strategies and innovations can be applied to other resource-limited settings, allowing the scaleup of health professional's training and research capacity building.

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“…Moreover, although there is an opportunity for local research teams to positively impact maternal sepsis management, challenges regarding institutional management and resource allocation, may hinder such improvement [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…Evidence shows that participation in a large multi-country study, like the Global Maternal Sepsis Study (GLOSS), [ 9 ] can potentially improve clinical management of patients [ 10 ] and enhance local research capacity. While GLOSS was not designed to intentionally build the capacities of local researchers, some specific activities (Additional file 1 ) allowed for capacity strengthening.…”

Section: Introductionmentioning

confidence: 99%

‘We always find things to learn from.’ Lessons from the implementation of the global maternal sepsis study on research capacity: a qualitative study

Compaoré

Brizuela

Khisa

et al. 2021

BMC Health Serv Res

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Background Research capacity strengthening could be an indirect outcome of implementing a research project. The objective of this study was to explore the ability of the global maternal sepsis study (GLOSS), implemented in 52 countries, to develop and strengthen sexual and reproductive health research capacity of local participants in low- and middle- income participating countries. Methods We carried out a qualitative study employing grounded theory in sixteen countries in Africa and Latin America. We used inductive and deductive methods through a focus group discussion and semi-structured interviews for the emergence of themes. Participants of the focus group discussion (n = 8) were GLOSS principal investigators (PIs) in Latin America. Interviewees (n = 63) were selected by the country GLOSS PIs in both Africa and Latin America, and included a diverse sample of participants involved in different aspects of study implementation. Eighty-two percent of the participants were health workers. We developed a conceptual framework that took into consideration data obtained from the focus group and refined it based on data from the interviews. Results Six themes emerged from the data analysis: recognized need for research capacity, unintended effects of participating in research, perceived ownership and linkage with the research study, being just data collectors, belonging to an institution that supports and fosters research, and presenting study results back to study implementers. Research capacity strengthening needs were consistently highlighted including involvement in protocol development, training and technical support, data analysis, and project management. The need for institutional support for researchers to conduct research was also emphasised. Conclusion This study suggests that research capacity strengthening of local researchers was an unintentional outcome of the large multi-country study on maternal sepsis. However, for sustainable research capacity to be built, study coordinators and funders need to deliberately plan for it, addressing needs at both the individual and institutional level.

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Participation in research improves overall patient management: insights from the Global Rheumatic Heart Disease registry (REMEDY)

Cited by 10 publications

References 11 publications

<p>Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study</p>

<p>Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study</p>

Design and Implementation of Postgraduate Programs in Health in a Resource-Limited Setting in Mozambique (The Lúrio University)

‘We always find things to learn from.’ Lessons from the implementation of the global maternal sepsis study on research capacity: a qualitative study

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