Particle size distributions of oil mists in workplace atmospheres and their exposure concentrations to workers in a fastener manufacturing industry

Chen, Mei‐Ru; Tsai, Perng Jy; Chang, Chih Ching; Shih, Tiffany Ting-Fang; Lee, Wen Jhy; Liao, Pao Chi

doi:10.1016/j.jhazmat.2006.12.036

Cited by 50 publications

(28 citation statements)

References 25 publications

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“…The results showed that 11.5% of the samples did not meet air quality standards. Long-term exposure to particulate matter may cause asthma, heart disease, laryngeal cancer, bronchial hyper-responsiveness, and lung cancer (Kazerouni et al, 2000;Davidsona et al, 2005;Chen et al, 2007;Buonanno et al, 2011;Wendt et al, 2014). Thus, it is very important to study airborne particulate matter in factories.…”

Section: Introductionmentioning

confidence: 99%

Strategy for Studying Ventilation Performance in Factories

Zhang

Long

Liu

et al. 2016

Aerosol Air Qual. Res.

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High concentrations of airborne particulate matter in factories can cause serious health problems for workers. One significant reason for these high concentrations is the poor performance of the ventilation systems in workplaces. This investigation developed a strategy that combines computational fluid dynamics (CFD) simulations and on-site measurements to study and improve the ventilation performance in factories. The CFD simulations were able to predict the flow field and particle distributions in factories with complex layouts. The corresponding on-site measurements were performed to provide boundary conditions for the CFD simulations and to obtain key data about airflow and air quality for validating the simulations. This study used the strategy to improve ventilation performance in an automotive parts factory. Three ventilation systems were studied: a roof exhaust system, combined roof exhaust and air recirculation systems, and combined roof exhaust and displacement ventilation systems. This study found that the combined roof exhaust and displacement ventilation systems provided acceptable indoor air quality and thermal comfort levels in the factory.

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Section: Introductionmentioning

confidence: 99%

Strategy for Studying Ventilation Performance in Factories

Zhang

Long

Liu

et al. 2016

Aerosol Air Qual. Res.

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“…Upon machining, mist or aerosol is spread through the air with dust and particles. Depending on size, particles can be inhaled and reach the alveoli and potentially increase risk of pulmonary injury [76]. Additionally, aldehydes, alkanolamines and volatile organic compounds can give rise to both respiratory and dermal health problems [66,77].…”

Section: Occupational Exposure To Metalworking Fluidsmentioning

confidence: 99%

Upper Airway Mucosal Inflammation : Proteomic Studies after Exposure to Irritants and Microbial Agents

Fornander¹

2015

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People are, in their daily lives, exposed to a number of airborne foreign compounds that do not normally affect the body. However, depending on the nature of these compounds, dose and duration of exposure, various airway symptoms may arise. Early symptoms are often manifested as upper airway mucosal inflammation which generates changes in protein composition in the airway lining fluid.This thesis aims at identifying, understanding mechanisms and characterizing protein alterations in the upper airway mucosa that can be used as potential new biomarkers for inflammation in the mucosa. The protein composition in the mucosa was studied by sampling of nasal lavage fluid that was further analyzed with a proteomic approach using two-dimensional gel electrophoresis and mass spectrometry. Additionally, by studying factors on site through environmental examination, health questionnaires and biological analyses, we have tried to understand the background to these protein alterations and their impact on health.Respiratory symptoms from the upper airways are common among people who are exposed to irritative and microbial agents. This thesis have focused on personnel in swimming pool facilities exposed to trichloramine, metal industry workers exposed to metalworking fluids, employees working in damp and moldy buildings and infants diagnosed with respiratory syncytial virus infection. The common denominator in these four studies is that the subjects experience upper airway mucosal inflammation, which is manifested as cough, rhinitis, phlegm etc. In the three occupational studies, the symptoms were work related. Notably, a high prevalence of perceived mucosal symptoms was shown despite the relatively low levels of airborne irritants revealed by the environmental examination. Protein profiling verified an ongoing inflammatory response by identification of several proteins that displayed altered levels. Interestingly, innate immune proteins dominated and four protein alterations occurred in most of the studies; SPLUNC1, protein S100A8 and S100A9 and alpha-1-antitrypsin. Similarly, these proteins were also found in nasal fluid from children with virus infection and in addition a truncated form of SPLUNC1 and two other S100 proteins (S100A7-like 2 and S100A16), not previously found in nasal secretion, were identified.Altogether, the results indicate the potential use of a proteomic approach for identifying new biomarkers for the upper respiratory tract at an early stage in the disease process after exposure to irritant and microbial agents. The results indicate an effect on the innate immunity system and the proteins; SPLUNC1, protein S100A8 and S100A9 and alpha-1-antitrypsin are especially promising new biomarkers. Moreover, further studies of these proteins may help us to understand the molecular mechanisms involved in irritant-induced airway inflammation. POPULÄRVETENSKAPLIG SAMMANFATTNING FÖRÄNDRAD PROTEINSAMMANSÄTTNING I DE ÖVRE LUFTVÄGARNA EFTER EXPONERING FÖR SLEMHINNEIRRITERANDE ÄMNENVarje dag utsätts vi för partikla...

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“…They are widely used in various fields for characterizing aerosols, such as environmental dust and haze (e.g., Kang et al, 2013), coals (e.g., Wang et al, 2007;Kazanc et al, 2013), urban aerosols (e.g., Maenhaut et al, 2002;Salma et al, 2002;Wagner et al, 2008;Xie et al, 2009), drugs (e.g., Klemmer et al, 2013;McBride et al, 2013;Sultana et al, 2013;Zhu et al, 2014), and bacterial aerosols (e.g., Simon et al, 2013;Li 2013). In addition, impactors are commonly used for characterizing workplace environments (e.g., Cohen and Powers 2000;Chen et al, 2007;Wu and Vincent, 2007;Dahlin et al, 2008a;Dahlin et al, 2008b;Dall'Osto et al, 2008;Linnainmaa et al, 2008;Birch et al, 2011;Yang 2011;Coggins et al, 2012;Ehrlich et al, 2013). Most of them (MOUDI, ELPI, DLPI, BLPI, QCM impactor, etc.)…”

Section: Introductionmentioning

confidence: 99%

Quantification of Low Pressure Impactor Wall Deposits during Zinc Nanoparticle Sampling

Durand

Bau

Moréle

et al. 2014

Aerosol Air Qual. Res.

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A Dekati® low pressure impactor (DLPI) is used to determine the mass distribution of airborne particles from 7 nm to 10 µm as a function of aerodynamic diameter. Quantification of wall deposits inside this sampling device was performed for the first time using polydisperse zinc aerosol produced by a thermal spraying process. This aerosol is more representative of the size distribution found in occupational atmospheres than aerosols usually produced in laboratories. Each experiment (3 replicates) was carried out for two durations. The results showed that wall deposits were quite considerable and in relation with aerosol modes. 13% and 14% of the total mass was found on the wall after sampling periods of 5 and 20 minutes, respectively. Relative losses could reach 50% for certain impaction stages and these losses were also quite different between replicates.

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Particle size distributions of oil mists in workplace atmospheres and their exposure concentrations to workers in a fastener manufacturing industry

Cited by 50 publications

References 25 publications

Strategy for Studying Ventilation Performance in Factories

Strategy for Studying Ventilation Performance in Factories

Upper Airway Mucosal Inflammation : Proteomic Studies after Exposure to Irritants and Microbial Agents

Quantification of Low Pressure Impactor Wall Deposits during Zinc Nanoparticle Sampling

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