On the Eastern Tauride Belt, the Cretaceous calc-alkaline Karamadazı Granitoid consists of quartz diorite containing mafic microgranular enclaves (MME) and leucocratic granite. The quartz diorite consists of plagioclase (An 8-65 ), hornblende, biotite, Kfeldspar, quartz, epidote and titanite. Subrounded MME in the quartz diorite are holocrystalline, finegrained, quartz diorite to diorite in composition, and display a similar mineral assemblage to their host. Large crystals in MME and quartz diorite show various disequilibrium microstructures indicative of hybridization. Plagioclase crystals exhibit inverse, normal, and oscillatory zoning with maximum core-to-rim An content increase up to 38% in the enclave and 40% in the quartz diorite. Both hornblende and augite exhibit normal and reverse zoning even in the same sample. The new field, textural, mineral compositional, and geochemical evidence leads to the conclusion that MME could have formed through injection of successive pulses of basic magma into upward mobile magma chambers containing cooler, partially crystalline quartz diorite magma. The quartz diorites show similarity to high-Al TTG (tonalites-trondhjemites-granodiorites), with their high Na 2 O, Sr, LREE, and low Mg#, Cr, HREE contents, and are suggested to be produced by extensive interaction between the crustal and mantlederived melts through mixing at depth. In contrast, leucogranites have geochemical characteristics distinct from the quartz diorites and MME, and are probably not involved in MME genesis.