Partnerships in Translation: Advancing Research and Clinical Care. The 14th Annual HMO Research Network Conference, April 13-16, 2008, Minneapolis, Minnesota

Greenlee, Robert T.; Coleman, Laura; Nelson, Andrew F.; Selby, Joseph V.

doi:10.3121/cmr.2008.842

Cited by 6 publications

(3 citation statements)

References 7 publications

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“…Data were derived from the CVRN LS‐ICD, a retrospective cohort study of primary prevention ICD implant patients recruited from seven healthcare delivery system members of the CVRN, affiliated with the Health Care Systems Research Network . Details of this study have been previously described .…”

Section: Methodsmentioning

confidence: 99%

“…Data were derived from the CVRN LS-ICD, a retrospective cohort study of primary prevention ICD implant patients recruited from seven healthcare delivery system members of the CVRN, 25 affiliated with the Health Care Systems Research Network. 26 Details of this study have been previously described. 27 Data for the LS-ICD were aggregated from three entities: the National Cardiovascular Data Registry (NCDR) ICD Registry (NCT01999140), the CVRN Virtual Data Warehouse (VDW), and an ICD device therapy data repository developed specifically for the LS-ICD.…”

Section: Study Design and Data Sourcesmentioning

confidence: 99%

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Influence of Multimorbidity on Burden and Appropriateness of Implantable Cardioverter‐Defibrillator Therapies

Hajduk

Gurwitz

Tabada

et al. 2019

J American Geriatrics Society

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OBJECTIVE To determine whether burden of multiple chronic conditions (MCCs) influences the risk of receiving inappropriate vs appropriate device therapies. DESIGN Retrospective cohort study. SETTING Seven US healthcare delivery systems. PARTICIPANTS Adults with left ventricular systolic dysfunction receiving an implantable cardioverter‐defibrillator (ICD) for primary prevention. MEASUREMENTS Data on 24 comorbid conditions were captured from electronic health records and categorized into quartiles of comorbidity burden (0‐3, 4‐5, 6‐7 and 8‐16). Incidence of ICD therapies (shock and antitachycardia pacing [ATP] therapies), including appropriateness, was collected for 3 years after implantation. Outcomes included time to first ICD therapy, total ICD therapy burden, and risk of inappropriate vs appropriate ICD therapy. RESULTS Among 2235 patients (mean age = 69 ± 11 years, 75% men), the median number of comorbidities was 6 (interquartile range = 4‐8), with 98% having at least two comorbidities. During a mean 2.2 years of follow‐up, 18.3% of patients experienced at least one appropriate therapy and 9.9% experienced at least one inappropriate therapy. Higher comorbidity burden was associated with an increased risk of first inappropriate therapy (adjusted hazard ratio [HR] = 1.94 [95% confidence interval {CI} = 1.14‐3.31] for 4‐5 comorbidities; HR = 2.25 [95% CI = 1.25‐4.05] for 6‐7 comorbidities; and HR = 2.91 [95% CI = 1.54‐5.50] for 8‐16 comorbidities). Participants with 8‐16 comorbidities had a higher total burden of ICD therapy (adjusted relative risk [RR] = 2.12 [95% CI = 1.43‐3.16]), a higher burden of inappropriate therapy (RR = 3.39 [95% CI = 1.67‐6.86]), and a higher risk of receiving inappropriate vs appropriate therapy (RR = 1.74 [95% CI = 1.07‐2.82]). Comorbidity burden was not significantly associated with receipt of appropriate ICD therapies. Patterns were similar when separately examining shock or ATP therapies. CONCLUSIONS In primary prevention ICD recipients, MCC burden was independently associated with an increased risk of inappropriate but not appropriate device therapies. Comorbidity burden should be considered when engaging patients in shared decision making about ICD implantation.

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Section: Methodsmentioning

confidence: 99%

Section: Study Design and Data Sourcesmentioning

confidence: 99%

Influence of Multimorbidity on Burden and Appropriateness of Implantable Cardioverter‐Defibrillator Therapies

Hajduk

Gurwitz

Tabada

et al. 2019

J American Geriatrics Society

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“…Partnerships in translation for advancing research and clinical care are likely to be important areas in which *This project was conducted by the European Regional Organization (ERO) Working Group 'The Relationship Between Dental Practitioners and Universities' and was presented at the ERO Plenary Session 2011, Sofia, Bulgaria. O R I G I N A L A R T I C L E further interaction is needed 9 , and community health efforts also require similar collaboration, partnerships and synergy among various stakeholders 6 . The same is true with regard to oral health and oral health services 5,10-12 .…”

mentioning

confidence: 99%

Collaboration between dental faculties and National Dental Associations (NDAs) within the World Dental Federation-European Regional Organization zone: an NDAs perspective

Yamalik

Mersel

Cavalle

et al. 2011

International Dental Journal

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Although improvements in certain oral health measures have been achieved, many global oral health matters and challenges exist. Collaborations and partnerships among various institutions are crucial in solving such problems. The main aim of the present study was to analyse the nature and extent of the partnership between dental faculties and National Dental Associations (NDAs). A questionnaire was developed, focusing on the relationship between NDAs and dental faculties within the World Dental Federation-European Regional Organization (FDI-ERO) zone with regard to major professional activities, such as dental education (both undergraduate and continuing education), workforce issues, improvement of national oral health, and science and knowledge transfer. The questionnaire was sent to all member NDAs within the ERO zone. The response rate was 21/41 (53.65%). The major activities in which NDAs were found to be involved were improvement of national oral health (100%), followed by continuing education activities (90%), whereas the activity which received least involvement was the development of an undergraduate dental curriculum (52%). The NDAs perceived their relationship with dental faculties to be quite satisfactory in the fields of continuing education, science and knowledge transfer, and the implementation of new technologies into daily dental practice. However, it was suggested that their relationship needed significant improvement with regard to the development of an undergraduate dental education curriculum, dental workforce issues and negotiations with the authorities regarding professional matters/issues. As the two important elements of organised dentistry, NDAs and dental faculties have a significant role to play in the improvement of oral health and in finding solutions to global oral health challenges; therefore, their collaboration and partnership are crucial for this purpose. On the basis of the perceptions of NDAs regarding their relationship with dental faculties, it can be concluded that their partnership can and should be further improved.

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Opioid Pharmacotherapy for Chronic Non-Cancer Pain in the United States: A Research Guideline for Developing an Evidence-Base

Chapman

Lipschitz

Angst

et al. 2010

The Journal of Pain

150

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Partnerships in Translation: Advancing Research and Clinical Care. The 14th Annual HMO Research Network Conference, April 13-16, 2008, Minneapolis, Minnesota

Cited by 6 publications

References 7 publications

Influence of Multimorbidity on Burden and Appropriateness of Implantable Cardioverter‐Defibrillator Therapies

Influence of Multimorbidity on Burden and Appropriateness of Implantable Cardioverter‐Defibrillator Therapies

Collaboration between dental faculties and National Dental Associations (NDAs) within the World Dental Federation-European Regional Organization zone: an NDAs perspective

Opioid Pharmacotherapy for Chronic Non-Cancer Pain in the United States: A Research Guideline for Developing an Evidence-Base

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