The integration of Marxism and Chinese excellent traditional culture is the basic experience and path of the modernization of the Chineseization of Marxism. This paper explores the integration of Marxism and Chinese excellent traditional culture based on the multiple linear regression model, explores the direct impact of Marxist Chineseization on Chinese excellent traditional culture with the fixed effect model, and adds control variables sequentially for stepwise regression to analyze the influencing factors of Chinese excellent traditional culture. Then the quantile regression model is further introduced to describe the differences in the marginal effect effects of the Chineseization of Marxism on the development of Chinese traditional culture under different level conditions. The non-linear characteristics of the effects and panel instrumental variables are tested using the panel threshold model and endogeneity estimation. The results indicate that Marxist Chineseization has a significant positive coefficient at the 1% level. Furthermore, the estimated coefficients of Marxist Chineseization are 0.016, 0.036, 0.067, 0.066, and 0.069 at 10%, 25%, 50%, 75%, and 90% quantile points, respectively, which are significantly positive, indicating that there exists a positive facilitating effect of Marxist Chineseization on the excellent traditional Chinese culture. This study is of great significance for promoting the Chineseization of Marxism and accelerating the modern transformation of traditional Chinese culture.