Passive mechanical properties of uterine muscle (myometrium) tested in vitro

Pearsall, G. W.; Roberts, Verne L.

doi:10.1016/0021-9290(78)90009-x

Cited by 52 publications

(36 citation statements)

References 9 publications

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“…They found that the outer layer was more compliant in compression, but was stiffer in tension [66]. The alignment of the smooth muscle fibers and the ECM along the long axis of the uterus is consistent with the uterine tissue being stiffer in tension.…”

Section: Mechanical Testing and Properties Of Uterinementioning

confidence: 75%

“…Like many other soft tissues, the mechanical behavior of cervical and uterine tissue is anisotropic, viscoelastic, and nonlinear elastic in addition to being heterogeneous [64,65]. Their properties are also asymmetric in tension versus compression [64,66].…”

Section: Mechanical Testing and Mechanical Properties Of Uterine And mentioning

confidence: 99%

“…There are no data available on animal uterine tissue, to the best of our knowledge. Uterine tissue has been tested in tension [66,69,70] and in static and dynamic compression [66,71] using either traditional mechanical testing system or ultrasound methods [72], as summarized in Table 2. While mechanical testing of uterine tissue in tension may yield the most physiologically [72] relevant data, these tests are difficult to conduct because of challenges associated with mounting tissue samples.…”

Section: Mechanical Testing and Properties Of Uterinementioning

confidence: 99%

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System-Level Biomechanical Approach for the Evaluation of Term and Preterm Pregnancy Maintenance

Mahmoud

Johnson

Chien

et al. 2013

Journal of Biomechanical Engineering

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Preterm birth is the primary contributor to perinatal morbidity and mortality, with those born prior to 32 weeks disproportionately contributing compared to those born at 32-37 weeks. Outcomes for babies born prematurely can be devastating. Parturition is recognized as a mechanical process that involves the two processes that are required to initiate labor: rhythmic myometrial contractions and cervical remodeling with subsequent dilation. Studies of parturition tend to separate these two processes rather than evaluate them as a unified system. The mechanical property characterization of the cervix has been primarily performed on isolated cervical tissue, with an implied understanding of the contribution from the uterine corpus. Few studies have evaluated the function of the uterine corpus in the absence of myometrial contractions or in relationship to retaining the fetus. Therefore, the cervical-uterine interaction has largely been neglected in the literature. We suggest that a system-level biomechanical approach is needed to understand pregnancy maintenance. To that end, this paper has two main goals. One goal is to highlight the gaps in current knowledge that need to be addressed in order to develop any comprehensive and clinically relevant models of the system. The second goal is to illustrate the utility of finite element models in understanding pregnancy maintenance of the cervical-uterine system. The paper targets an audience that includes the reproductive biologist/clinician and the engineer/physical scientist interested in biomechanics and the system level behavior of tissues.

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Section: Mechanical Testing and Properties Of Uterinementioning

confidence: 75%

Section: Mechanical Testing and Mechanical Properties Of Uterine And mentioning

confidence: 99%

Section: Mechanical Testing and Properties Of Uterinementioning

confidence: 99%

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System-Level Biomechanical Approach for the Evaluation of Term and Preterm Pregnancy Maintenance

Mahmoud

Johnson

Chien

et al. 2013

Journal of Biomechanical Engineering

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“…Surface area of the placenta was 26866 mm 2 at the utero-placental interface (UPI). The placenta was 4(9) modelled as elastic isotropic solid material; its properties were taken from Pearsall and Roberts [11], having a Poisson's ratio of 0.49, Young's modulus of 47kPa and a density of 0.995kg/dm 3 .…”

Section: Placenta Modellingmentioning

confidence: 99%

“…The abdomen may be different not only from one woman to another but also from one pregnancy to another for the same woman. In approximately 80 % of pregnancies, the placenta is located in the upper region (fundus) of the uterus (Pepperell et al, [12] ) hence the previous studies focused on the fundus location of the placenta only (Rupp et al, [11] and Acar and Esat [3] ) However, placenta can be attaced anywhere on the inner surface of the uterus wall, such as anterior or posterior, lateral left or lateral right. Placenta may also be attached to the uterine wall covering cervix however, this is very rare, occurring in less than 1% of all pregnancies.…”

Section: Introductionmentioning

confidence: 99%

The effect of placenta location on the safety of pregnant driver and her fetus

Açar

Meric

2016

International Journal of Crashworthiness

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Citation: ACAR, B. and MERIC, M., 2016. The effect of placenta location on the safety of pregnant driver and her fetus. International Journal of Crashworthiness, 22 (2), pp.163-168. ABSTRACTPlacental abruption accounts for more than half of fetal mortality in automobile collisions. In most of the pregnancies, placenta is located at the fundus position of the uterus. However, in real life, placenta can also be found at different locations in the uterus.The goal of this study is to investigate whether the location of the placenta in the uterus of pregnant driver has a role on the risk of placental abruption in motor vehicle accidents. In addition to the most common fundus position, four other placental locations namely, anterior, posterior, lateral left and lateral right, are considered within the computational pregnant driver model 'Expecting', and used in collision simulations with impact severities from 15 kph to 30 kph with 5kph increments. Scenarios also include four cases where the pregnant driver is fully restrained with three-point seatbelt and airbag, three-point seatbelt only, airbag only and no-restraint at all.The maximum strains developed in the utero-placental interface (UPI) of the model in this set of 64 simulations together with the fundus-location simulations are determined and compared in order to investigate the effect of placental location on the placental abruption prediction.Placenta located at anterior position is found to be at higher risk than other placental positions considered in this investigation. The results demonstrate that being fully restrained is the safest option and the three-point seatbelt is the most effective restraint system whilst the airbag makes a small contribution to the protection of pregnant driver and her fetus.

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