Passive smoking induces nasal biofilms in children

Elwany, Samy; Gamea, Mohamed; Talaat, Iman M.

doi:10.1016/j.ijporl.2021.110755

Cited by 7 publications

(8 citation statements)

References 17 publications

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“…(± 15.6). Children of the study group who developed nasal biofilms were exposed to tobacco smoke for significantly longer duration than children who did not develop biofilms, moreover children of heavy smokers, (those who smoke greater than or equal to 25 or more cigarettes a day) developed nasal biofilms more frequently than other children (6).…”

Section: Description Of the State Of Knowledgementioning

confidence: 89%

“…The nose and paranasal sinuses are exposed to significantly higher levels of particle pollution than the lower respiratory tract (19). Tobacco smoke and CRS have been associated because of the immunosuppressive and irritating effects of tobacco smoke on sinonasal epithelial cells (6). Bioactive components of tobacco smoke triggered the formation of S. aureus biofilms through an oxidant-dependent mechanism, according to Kulkarni et al (10).…”

Section: Description Of the State Of Knowledgementioning

confidence: 99%

“…In the study by Elwany et al, they performed identification of biofilms for report about development of nasal biofilms in children exposed to household passive smoking (6). A questionnaire study among parents and an objective study of cotinine in the urine of children confirmed the exposure of children to passive smoking.…”

Section: Description Of the State Of Knowledgementioning

confidence: 99%

“…Biofilms are known to be related with various infections, including chronic rhinosinusitis, otitis media, and pneumonia. Worth mentioning is that biofilms have inherent resistance to the human immune system and antimicrobial drugs (4,6).…”

Section: Introduction and Purposementioning

confidence: 99%

“…In 2020, tobacco was used by 22.3 percent of the global population (11). Inhaling smoke or tobacco products produced by others is known as passive or second-hand smoking (PS) (6). The non-smoker breathes sidestream smoke from the cigarette's burning tip, as well as mainstream smoke inhaled and expelled by the smoker.…”

Section: Introduction and Purposementioning

confidence: 99%

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The correlation between second-hand tobacco smoke exposure and biofilm formation in chronic rhinosinusitis

Standyło

Obuchowska

Mielnik–Niedzielska

2022

J Educ Health Sport

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Introduction and purpose Tobacco smoke is a major health concern globally. Due to tobacco epidemic, approximately 8 million people died as a result of cigarette smoking in 2020 alone, where 1.2 million were caused by non-smokers inhaling second-hand smoke. Chronic rhinosinusitis (CRS) is an inflammatory condition that has a significant health and economic impact worldwide. Despite its great burden on the health-care system and patients' quality of life, the variety of therapy options for CRS is currently limited. Tobacco-induced biofilm formation may contribute to the refractory nature of many respiratory diseases reported in smokers and second-hand smokers, due to increased resistance to antibiotics. The aim of this study is to present that exposure to household passive smoking may induce the formation of nasal biofilms. Brief description of the state of knowledge Chronic bacterial infections involving biofilms have recently been recognised as a factor in CRS pathogenesis. The presence of biofilms on the mucosa of CRS patients is associated with more severe pre-operative disease, persistent postoperative symptoms, ongoing mucosal inflammation, and infections following endoscopic sinus surgery. Tobacco smoke and CRS have been associated because of the immunosuppressive and irritating effects of tobacco smoke on sinonasal epithelial cells. Smoking uptake and cessation have been shown to affect microbial communities, with smokers having not just distinct microbial communities, but also a higher frequency of possible pathogens in those communities. Summary Biofilms may play a significant role in the development of chronic rhinosinusitis. The impact of tobacco smoke on biofilm development could have major implications not only for CRS but also for other respiratory infections.

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Section: Description Of the State Of Knowledgementioning

confidence: 89%