Pasteur : premier des post-pasteuriens ?

Guglielmo, Marine de

doi:10.4000/rac.24500

rac

2021

DOI: 10.4000/rac.24500

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Pasteur : premier des post-pasteuriens ?

Marine de Guglielmo¹

Abstract: Ce texte vise à discuter le clivage historique et anthropologique proposé par les auteurs contemporains Heather Paxson et Jamie Lorimer, entre l'ère « pasteurienne » et l'ère « post-pasteurienne » ou bien encore entre l'ère « antibiotique » et l'ère « probiotique ». Nous proposons ainsi une relecture du travail de Pasteur et de ses collaborateurs, dans le but de questionner l'antagonisme qui l'opposerait au « post-pasteurisme » contemporain.

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2023

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Between the genotype and the phenotype lies the microbiome: symbiosis and the making of ‘postgenomic’ knowledge

Fasel,

Chiapperino

2023

HPLS

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Emphatic claims of a “microbiome revolution” aside, the study of the gut microbiota and its role in organismal development and evolution is a central feature of so-called postgenomics; namely, a conceptual and/or practical turn in contemporary life sciences, which departs from genetic determinism and reductionism to explore holism, emergentism and complexity in biological knowledge-production. This paper analyses the making of postgenomic knowledge about developmental symbiosis in Drosophila melanogaster by a specific group of microbiome scientists. Drawing from both practical philosophy of science and Science and Technology Studies, the paper documents epistemological questions of artefactuality and representativeness of model organisms as they emerge in the day-to-day labour producing and being produced by the “microbiome revolution." Specifically, the paper builds on all the written and editorial exchanges involved in the troubled publication of a research paper studying the symbiotic role of the microbiota in the flies’ development. These written materials permit us to delimit the network of justifications, evidence, standards of knowledge-production, trust in the tools and research designs that make up the conditions of possibility of a postgenomic fact. More than reframing the organism as a radically novel multiplicity of reactive genomes, we conclude, doing postgenomic research on the microbiota and symbiosis means producing a story that deviates from the scripts embedded into the sociotechnical experimental systems of post-Human Genome Project life sciences.

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Between the genotype and the phenotype lies the microbiome: symbiosis and the making of ‘postgenomic’ knowledge

Fasel,

Chiapperino

2023

HPLS

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Pasteur : premier des post-pasteuriens ?

Cited by 1 publication

References 10 publications

Between the genotype and the phenotype lies the microbiome: symbiosis and the making of ‘postgenomic’ knowledge

Between the genotype and the phenotype lies the microbiome: symbiosis and the making of ‘postgenomic’ knowledge

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