Pasteurella multocida Toxin Type D Serological Assay as an Alternative to the Toxin Neutralisation Lethality Test in Mice

Finco‐Kent, Deborah; Galvin, Jeffrey E.; Suiter, B. T.; Huether, Michael J.

doi:10.1006/biol.2001.0268

Biologicals

2001

DOI: 10.1006/biol.2001.0268

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Pasteurella multocida Toxin Type D Serological Assay as an Alternative to the Toxin Neutralisation Lethality Test in Mice

Deborah Finco‐Kent

Jeffrey E. Galvin

B. T. Suiter

et al.

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Cited by 3 publications

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“…Pasteurella multocida is pathogenic to mice. The mouse lethality test involves injecting mice with the vaccine before administration of the bacterial culture and determining the mortality percentage[29]. The vaccination induces humoral immunization.…”

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confidence: 99%

Immunomodulatory potential of methanol extract of Aegle marmelos in animals

Govinda¹,

Asdaq²

2011

Indian J Pharm Sci

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The aim of the current research was to evaluate the immunomodulatory potential of methanol extract of Aegle marmelos in an experimental animal model of cellular and humoral immunity. Administration of methanol extract of Aegle marmelos (500 and 1000 mg/kg, p.o.) and Ocimum sanctum (100 mg/kg, p.o.), produced significant increase in adhesion of neutrophils and an increase in phagocytic index in carbon clearance assay. Both doses of Aegle marmelos prevented the mortality induced by bovine Pasteurella multocida in mice. Moreover, all treated groups demonstrated significant elevation in circulating antibody titre in the indirect haemagglunation test. From the above results, it can be concluded that methanol extract of Aegle marmelos possess immunomodulatory potential by stimulating cellular and humoral immune mechanisms. However, low dose of methanol extract of Aegle marmelos was more effective for augmenting cellular immunity, whereas, high dose was more inclined towards humoral immunity.

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mentioning

confidence: 99%

Immunomodulatory potential of methanol extract of Aegle marmelos in animals

Govinda¹,

Asdaq²

2011

Indian J Pharm Sci

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Immunomodulatory activity of methanolic fruit extract of Aegle marmelos in experimental animals

Patel¹,

Asdaq²

2010

Saudi Pharmaceutical Journal

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Evaluation of immunomodulatory effects of lomefloxacin in mice

Majeed

Javeed

Omer

et al. 2020

Braz. J. Pharm. Sci.

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Pasteurella multocida Toxin Type D Serological Assay as an Alternative to the Toxin Neutralisation Lethality Test in Mice

Cited by 3 publications

References 9 publications

Immunomodulatory potential of methanol extract of Aegle marmelos in animals

Immunomodulatory potential of methanol extract of Aegle marmelos in animals

Immunomodulatory activity of methanolic fruit extract of Aegle marmelos in experimental animals

Evaluation of immunomodulatory effects of lomefloxacin in mice

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