The increasing demand for wireless communication underscores the necessity for effective RF energy harvesting solutions, particularly within the burgeoning WiFi 6E spectrum (5.925–7.125 GHz). This paper details the design and evaluation of a compact slotted patch antenna with partial grounding specifically optimized for RF energy harvesting in this frequency range. The objective is to create a high-performance antenna with a wide bandwidth, making it ideal for integration into energy-harvesting devices. The antenna features a slotted patch configuration combined with a partial grounding approach and is constructed on an FR4 substrate measuring 9.18 × 9.18 × 1.6 mm³. This substrate has a dielectric constant of 4.3, a thickness of 1.6 mm, and a tangent loss of 0.025. A 50-Ohm microstrip line is used for feeding the antenna. Simulations performed using CST Microwave Studio reveal remarkable performance characteristics, including a reflection coefficient (S11) of -34.02739 dB, a Voltage Standing Wave Ratio (VSWR) of 1.040519, and a bandwidth of 2.22396 GHz, extending from 4.948941 GHz to 7.172901 GHz. Additionally, the antenna demonstrates a gain of 0.276 dBi, a directivity of 2.98 dBi, and an efficiency of-2.702 dB (53.68%). These findings indicate that the antenna is well-suited for energy-harvesting applications within the WiFi 6E band. Its compact dimensions, high efficiency, and broad bandwidth position it as a promising option for a variety of applications, including wireless sensor networks, wearable devices, and Internet of Things (IoT) systems, all of which depend significantly on energy harvesting for self-sustained operation.