Patch Test as a Diagnostic Tool in  Hand Eczema

Vigneshkarthik, Natarajan; Ganguly, Satyaki; Kuruvila, Sheela

doi:10.7860/jcdr/2016/23994.8884

Cited by 12 publications

(19 citation statements)

References 13 publications

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“…Detergents are an important source of sensitization, proven by positive patch test results to nickel, cobalt and PPD among patients with history of exposure to detergents. 25 In many wet work occupations, lipid soluble chemicals are added to water to achieve the cleaning effect. These chemicals wash away intracellular lipids.…”

Section: Discussionmentioning

confidence: 99%

Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

Qayoom¹,

Rather²,

Khan³

2018

Int J Res Med Sci

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Background: Hand eczema is a common dermatological disorder in different occupational groups with multifactorial etiology. Patch Testing serves as an important tool for identifying responsible allergens.Methods: The study was conducted in the Department of Dermatology, SKIMS-MCH, Srinagar for duration of one year from June 2016 to June 2017. Patients of either gender with hand eczema, aged 18 years and above, presenting to outpatient department were enrolled in the study. After taking informed written consent from patients, a detailed history was taken, and clinical examination was performed on first visit. Patch testing with Indian Standard Series was performed a fortnight after complete resolution of signs and symptoms of eczema and after complete withdrawal of the drugs.Results: Out of 116 patients 60 (51.7%) were males and 56 (48.3%) were females. Male to female ratio was 1.07:1. Mean age of presentation of females was 35.42±12.52years and of males was 49.2±10.01years. The commonest allergen was Nickel sulphate (23.2%) followed by Potassium dichromate (15.1%). Nickel sulphate was most common allergen in females while Cobalt sulphate and Paraphenylene diamine were most common allergens in males. House wives (36.2%) and farmers (11.2%) were occupations with high frequency of hand eczema.Conclusions: Patch testing in clinically diagnosed cases of hand eczema can play a vital role in not just the confirmation of the label but can also reduce the socio-economic burden on such patients.

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Section: Discussionmentioning

confidence: 99%

Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

Qayoom¹,

Rather²,

Khan³

2018

Int J Res Med Sci

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“…irritant contact dermatitis, allergic contact dermatitis, contact urticaria), commonly on hands but also on other body parts (e.g. forearms, face and neck) ( 4 , 5 ). Skin contact reactions may be characterized by different clinical features including itching, erythema, papulovesicles, fissuring, hyperkeratosis and lichenification but also as urticarial lesions ( 2 , 3 ).…”

Section: Introductionmentioning

confidence: 99%

“…We should not neglect the fact that geographical, occupational, economic and even social factors can result in different exposures to irritants/allergens and, consequently, patterns of contact dermatitis which can differ from one part of the world to another ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Analysis of Dental Professionals’ and Dental Students’ Care for their Skin

Japundžić¹,

Novak

Kuna

et al. 2018

Acta Stomatol Croat

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ObjectivesTo determine prevalence of undesirable, work-related skin lesions and their localizations in dental professionals and students, and to collect data about diagnostic procedures they undergo and skin care they take when these lesions occur.Subjects and methodsOur research included 444 respondents (dentists, dental assistants, dental technicians, dental students) who filled out a questionnaire. They were asked to specify if they had observed any lesions on their skin and where; if they had undergone any treatments and in what way; if they had undergone any allergy tests; and if they had taken any protective measures.ResultsOf all the respondents that took part in the survey, 249 (56.1%) reported undesirable skin reactions commonly on their hands and fingers (96%). Before our survey, only 15% of them had seen a dermatologist, while 33% had undergone allergy tests (without a dermatologists’ clinical examination). Also, 45% of them sometimes used soaps for sensitive skin and the majority (61%) of them used protective hand creams 1-2 times per day.ConclusionAlthough a large number of dental professionals and students have noticed work-related skin lesions, only some of them sought dermatologists’ professional help and most of them did not take care of their skin adequately when those lesions occurred. According to the results of this study, it is necessary to take additional preventive measures to increase dental professionals’ and students’ awareness of occupational dermatoses and adequate skin care.

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“…[13] Contact allergens play an important role in the etiology of hand eczemas, including chronic vesicular dermatitis. [914] Other factors include a correlation with smoking and a flare on oral challenge with metal salts. [415]…”

Section: Discussionmentioning

confidence: 99%

Common contact allergens in patients with chronic vesicular dermatitis of palms and soles: A retrospective study

Gupta¹,

Pruthi²,

Kumar

et al. 2019

Indian Dermatol Online J

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Background: Chronic and recurrent vesiculation over the palms and soles is termed chronic vesicular dermatitis. Its etiology is multifactorial and contact allergy plays an important role. Aim: The aim of the study is to evaluate the clinical relevance of patch test reactivity to common contact allergens in chronic palmoplantar vesicular dermatitis. Materials and Methods: An observational study was conducted enrolling 152 patients of chronic palmoplantar vesicular dermatitis. Patch testing was carried out with the Indian Standard Battery and also with the materials used by patients. Statistical analysis was carried out using SPSS software. Results: Among 152 patients, 91 were female and 61 male. The peak incidence was in the 14–24 years age group. Their occupations included housewives 48, laborers 26, factory workers 16, farm workers 14, and shopkeepers 12. Patch tests were positive in 79 (52%) patients, including 43 (28.3%) female and 36 (23.7%) male. Patch test reactivity was observed with nickel in 25 (16.4%); potassium dichromate in 21 (13.8%); fragrance mix in 17 (11.2%); p -phenylenediamine in 14 (9.2%); black rubber in 10 (6.6%); mercaptobenzothiazole in 8 (5.3%); and parthenium in 8 (5.3%) patients. Clinical relevance of positive patch tests was determined in 47 (59.5%) patients. Conclusions: Though patch test reactivity was higher in females as compared with males, the difference was not statistically significant. Clinical relevance of positive patch tests was established with nickel in 9 (19.1%) patients; antigens associated with rubber including black rubber, mercaptobenzothiazole, and thiuram mix in 7 (14.9%); potassium dichromate in 7 (14.9%); p -phenylenediamine in 6 (12.8%); and parthenium in 4 (8.5%) patients.

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Patch Test as a Diagnostic Tool in Hand Eczema

Cited by 12 publications

References 13 publications

Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

Analysis of Dental Professionals’ and Dental Students’ Care for their Skin

Common contact allergens in patients with chronic vesicular dermatitis of palms and soles: A retrospective study

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