Patch-Test Results of an Academic Department in Izmir, Turkey

Ertam, İlgen; Türkmen, Mutlu; Alper, Sibel

doi:10.2310/6620.2008.08004

Cited by 24 publications

(60 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The results of the present study show a high prevalence of MCI/MI and MI contact allergy in Turkey, similarly to the existing reports from Europe . The previous studies from Turkey have reported a sensitization rate of ≤1% for MCI/MI, but, to the best of our knowledge, there are no data on MI sensitization rates. In accordance with the recent reports, we also observed a decrease in the prevalence of MCI/MI and MI contact allergy from 2016 to 2018.…”

Section: Discussionsupporting

confidence: 88%

Methylchloroisothiazolinone and methylisothiazolinone contact allergy: A retrospective cohort study from a tertiary dermatology clinic in Turkey

Salman

2018

Contact Dermatitis

View full text Add to dashboard Cite

Funding informationNone K E Y W O R D S : contact allergy, methylchloroisothiazolinone, methylisothiazolinone, Turkey Isothiazolinones, that is, methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI), are widely used preservatives in cosmetic, industrial and household products, owing to their strong biocidal effects. 1 Following an epidemic of contact allergy to MCI/MI (Kathon CG) and subsequent regulatory measures regarding the use of MCI/MI, the use of MI as a monopreservative has increased. The reports of contact allergy to MI during the mid-2000s led to further limitations on the use of MI in cosmetic products, and MI was added to the European baseline series in 2015. 2-5 Despite the vast amount of data from different countries, there are still, to our knowledge, no data on MCI and MI contact allergy in Turkey. Thus, the aim of the present study was to investigate the frequency, and demographic and clinical features, of MCI/MI and MI contact allergy in a tertiary dermatology centre in Turkey. PATIENTS AND METHODSA retrospective study was performed. Medical records of all patients who had been tested with the European baseline series in our contact dermatitis outpatient clinic between January 2016 and June 2018were reviewed. Patients were tested with allergens (MCI/MI 0.02% aq. and MI 0.2% aq.) and IQ Ultra chambers obtained from Chemotechnique Diagnostics (Vellinge, Sweden). Readings were performed on day (D) 2 and D4, according to ESCD guidelines. 6 The study protocol was reviewed and approved by our institution's ethics committee. RESULTSA total of 324 patients were patch tested during the study period. Of them, 29 (8.9%) had positive reactions to MCI/MI and/or MI. The rate of positive reactions to MCI/MI and MI showed a decrease during the TABLE 1 The frequency of methylchloroisothiazolinone (MCI)/ methylisothiazolinone (MI) and MI contact allergy and the change over the years Years 2016 n (%) 2017 n (%) 2018 n (%) Total n (%) Total number of patients 128 108 89 324 MCI/MI positive 8 (6.25) 7 (6.48) 5 (5.61) 20 (6.17) MI positive 12 (9.37) 9 (8.33) 5 (5.61) 26 (8.02) Both positive 7 (5.46) 6 (5.55) 4 (4.49) 17 (5.24) MCI/MI and/or MI positive 13 (10.15) 10 (9.25) 6 (6.74) 29 (8.95) SALMAN 193

show abstract

Section: Discussionsupporting

confidence: 88%

Methylchloroisothiazolinone and methylisothiazolinone contact allergy: A retrospective cohort study from a tertiary dermatology clinic in Turkey

Salman

2018

Contact Dermatitis

View full text Add to dashboard Cite

show abstract

“…Overall, the frequency of positive patch test reactions among persons with suspected nickel dermatitis varies from 0.5 to 8.5% for males and reaches 43% in females 8 . In addition, younger age seems to favor the development of nickel contact allergy 9,10 . A possible explanation for this phenomenon is exposure to nickel‐containing materials in younger groups, such as ear piercing and jewelry 11,12 .…”

Section: Epidemiologymentioning

confidence: 99%

The many faces of nickel allergy

Darlenski

Kazandjieva²,

Pramatarov

2012

Int J Dermatology

View full text Add to dashboard Cite

Hypersensitivity reactions to nickel are one of the most common in the modern world. Nickel allergy prevalence is constantly growing in many countries and represents a major health and socioeconomic issue. Herein the current understanding on nickel allergy is summarized with a practical approach to the dermatologist, allergist, and general practitioner. The personal experience with some practical clinical cases of nickel dermatitis is shared. A special emphasis is put on the possible strategies for treatment and prevention of the disease.

show abstract

“…7 Şimdiye kadar yama testi sonuçlarını içeren ülkemizin çeşitli bölgelerinden bildirilen bazı çalışmalar mevcuttur. [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] Yaptığımız literatür tara-masında, Malatya ve çevre illerde AKD'li hastalarda yama testi üzerine yapılmış bir çalışmaya rastlanmamıştır.…”

unclassified

“…Yapılan çalışmalarda, nikel alerjisi oranı %12-29,6 arasında değişmektedir. [10][11][12][13][14][15][16][17][18][19][20][21] Nikel alerjisinin kadınlarda daha sık olduğu görülmektedir. Bu çalışmada kadınların %23,3'ünde nikele karşı alerji oluşur iken, erkeklerin %6,5'inde duyarlanma saptanmıştır.…”

unclassified

“…Ülkemizdeki diğer çalışmalarda da potasyum dikromata karşı alerjinin ilk üç sıra içerisinde olduğu görülmekte ve duyarlanma oranları %2,2-16,5 arasında değişmektedir. [11][12][13][14][15][16][17][18][19][20] İllere göre oluşan farklar, bulunulan bölgede inşaat sektörünün yaygınlığı ile alakalı olabilmektedir. Çalışmamızda yer alan ve inşaat sektöründe çalışan dört hastanın yarısında duyarlanma mevcuttu.…”

unclassified

See 1 more Smart Citation

Patch Test Results in 169 Patients with Allergic Contact Dermatitis in Malatya

Türkmen¹,

Altunışık²

2018

Turkiye Klinikleri J Dermatol

View full text Add to dashboard Cite

Ö ÖZ ZE ET T A Am ma aç ç: : Alerjik kontakt dermatit (AKD); alerjen madde ile daha önceden duyarlanmış kişinin aynı madde ile tekrar karşılaşması sonucu ortaya çıkan, gecikmiş tip reaksiyondur. AKD'ye neden olabilecek alerjenler coğrafi ve toplumsal farklılıklar gösterebilmektedirler. Malatya ve çevre illerde bu konuda daha önce yapılmış bir çalışma olmaması nedeni ile bölgemizdeki alerjen profili hakkında bilgilendirme amacıyla bu çalışma hazırlanmıştır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Kliniğimize başvuran ve AKD tanısı alan 169 hasta çalışmada yer aldı. Hastaların tümüne standart seri alerjenlerini içeren, toplam 36 alerjenden oluşan "thin layer-rapid-use-epicutaneous" test uygulandı. Değerlendirmede reaksiyon yok ise (-); hafif eritem, şüpheli reaksiyon (+/-); eritem, infiltrasyon (+); eritem, infiltrasyon, papül, vezikül (++); eritem, infiltrasyon, bül (+++) şeklinde yapıldı. Hasta dosyaları retrospektif olarak incelenip; yaş, cinsiyet, meslek ve deri yama testinde saptanan reaksiyonla ilgili bilgiler kaydedildi. B Bu ul lg gu ul la ar r: : Çalışmaya dâhil edilen 169 hastanın 91 (%53,8)'i kadın, 78 (%46,2)'i erkek idi. Yaş ortalaması 38,09±15,69 yıldı. Hastaların %27,8'inin ev hanımı, %20,1'inin öğrenci, %11,8'inin memur, %8,9'unun işçi, %7,1'inin sağlık çalışanı olduğu belirlendi. Hastaların %45'inde yama testinde en az bir alerjene karşı pozitif reaksiyon saptandı. En sık beş alerjen; nikel sülfat (%16), potasyum dikromat (%8,3), tiyomersal (%7,1), altın sodyum tiyosülfat (AST) (%7,1) ve karbamat karışımı (%6,5) oldu. Kadınlarda en sık saptanan alerjenler nikel sülfat ve AST iken, erkeklerde potasyum dikromat ve karbamat karışımı idi. S So on nu uç ç: : İlimizde ve çevre illerde bizden önce yama testi ile ilgili bir çalışma yapılmamış olması sebebiyle bu çalışma, Malatya ilinde AKD tanısı konup yama testi yapılan hastalardaki alerjen profili hakkında faydalı bir bilgi sunmaktadır.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Alerjik kontak dermatit; yama testi A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : Allergic contact dermatitis (ACD) is a delayed type reaction that occurs when an allergen is previously sensitized to the same substance. Allergens which may cause ACD may show geographical and social differences. This article has been prepared for the purpose of informing about the allergen profile in our region since there is no previous study on this subject in Malatya and the surrounding provinces. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : A total of 169 patients who presented to our clinic and were diagnosed with ACD were included in the study. Thin layer-rapiduse-epicutaneus test consisting of 36 allergens was applied to all patients with standard series allergens. In the evaluation no reaction (-); mild erythema, suspected reaction (+/-); erythema, infiltration (+); erythema, infiltration, papule, vesicle (++); erythema, infiltration, bulla (+++). Patient files were retrospectively reviewed and information about the reaction detected in ...

show abstract

Patch-Test Results of an Academic Department in Izmir, Turkey

Cited by 24 publications

References 2 publications

Methylchloroisothiazolinone and methylisothiazolinone contact allergy: A retrospective cohort study from a tertiary dermatology clinic in Turkey

Methylchloroisothiazolinone and methylisothiazolinone contact allergy: A retrospective cohort study from a tertiary dermatology clinic in Turkey

The many faces of nickel allergy

Patch Test Results in 169 Patients with Allergic Contact Dermatitis in Malatya

Contact Info

Product

Resources

About