Patent foramen ovale: A new disease?

Drighil, A.; Mosalami, Hanane El; Elbadaoui, Nadia; Chraibi, Saïd; Bennis, Ahmed

doi:10.1016/j.ijcard.2006.12.028

Cited by 38 publications

(40 citation statements)

References 105 publications

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“…This should prompt the clinician to request an echocardiogram with a bubble test (administration of agitated saline through a peripheral vein), preferably a transesophageal one [60]. The passage of microbubbles to the left atrium in the first three beats after right-cavity opacification confirms the diagnosis; some authors demand detection of ≥5 bubbles in the left atrium, but this and the place of injection are not standardized [61]. The appearance of microbubbles following the third beat usually corresponds to intrapulmonary shunting.…”

Section: Methodsmentioning

confidence: 99%

Platypnea-Orthodeoxia Syndrome in Review: Defining a New Disease?

Rodrigues¹,

Palma²,

Sousa-Pereira³

2012

Cardiology

127

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Platypnea-orthodeoxia syndrome is an intriguing condition that comprehends multiple pathologic phenomena. It requires a high clinical suspicion and is probably underdiagnosed. Its identification has therapeutic implications and can have a huge impact on the patient’s everyday life. We made a review of the literature and analyzed 188 cases described thus far, trying to identify the underlying mechanisms and risk factors. We propose that a separate entity is created within the spectrum of platypnea-orthodeoxia syndrome that is responsible for the majority of cases, namely platypnea-orthodeoxia disease, which would be defined as the existence of an interatrial communication, with a right-to-left shunt, normal pressure in the right atrium and, of course, platypnea and orthodeoxia. Most patients with this disease were submitted to percutaneous closure of the patent foramen ovale or atrial septal defect, with favorable results, making it the first-line therapeutic approach nowadays.

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Section: Methodsmentioning

confidence: 99%

Platypnea-Orthodeoxia Syndrome in Review: Defining a New Disease?

Rodrigues¹,

Palma²,

Sousa-Pereira³

2012

Cardiology

127

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“…В многочисленных публикациях отмечалось значительное преобладание числа больных с ООО среди перенесших ин-сульт по сравнению с распространенностью данной анома-лии в общей популяции [21,22]. Недавние исследования продемонстрировали, что увеличение риска церебральных эмболических событий находится в прямой зависимости от размера ООО, оцененного с помощью чреспищеводной эхокардиографии.…”

Section: ла гераскинаunclassified

Cardioembolic stroke: a variety of causes and current approaches to its prevention

Гераскина

2013

Neurology, Neuropsychiatry, Psychosomatics

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“…However, contrast is still valuable in difficult cases in whom it is often coupled with the Valsalva manoeuvre which increases the amount of shunting when the abdominal pressure is released [89]. This method has become more important with the realisation that persistent foramen ovale occurs in 25% of adults and can be responsible for paradoxical embolisation that causes stroke, especially in younger people [31,56]. Contrast used during transoesophageal echocardiography is also useful in this problem [85].…”

Section: The Heartmentioning

confidence: 99%