Pathogenesis and immunopathology of paraneoplastic disorders

Quinot, Valérie; Höftberger, Romana

doi:10.1016/b978-0-12-823912-4.00027-x

Handbook of Clinical Neurology

2024

DOI: 10.1016/b978-0-12-823912-4.00027-x

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Pathogenesis and immunopathology of paraneoplastic disorders

Valérie Quinot,

Romana Höftberger

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2025

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Selected Aspects of the Neuroimmunology of Cell Therapies for Neurologic Disease

Ransohoff

2025

Neurol Neuroimmunol Neuroinflamm

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Neurologic disease remains a cause of incalculable suffering, a formidable public health burden, and a wilderness of complex biology and medicine. At the same time, advances in basic science, technology, and the clinical development toolkit bring meaningful benefit for patients along with realistic hope for those whose conditions remain inadequately treated. This perspective focuses on cell-based therapies for neurologic disease, with particular emphasis on neuroimmunologic disorders and on the immunologic considerations of cell therapy for nonimmune conditions. I will consider the use of chimeric antigen receptor (CAR)-T effector cells and regulatory T-cell therapies for autoimmune conditions. I will briefly discuss the immune aspects of pluripotent stem cell (PSC)–derived neuronal therapies. With apologies for the omission, we do not discuss mesenchymal stem cells, glial progenitor cells, or CAR-NK cells, primarily for space limitations.

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Selected Aspects of the Neuroimmunology of Cell Therapies for Neurologic Disease

Ransohoff

2025

Neurol Neuroimmunol Neuroinflamm

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show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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Pathogenesis and immunopathology of paraneoplastic disorders

Cited by 1 publication

References 169 publications

Selected Aspects of the Neuroimmunology of Cell Therapies for Neurologic Disease

Selected Aspects of the Neuroimmunology of Cell Therapies for Neurologic Disease

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