Oxford Handbook of Genitourinary Medicine, HIV, and Sexual Health 2010
DOI: 10.1093/med/9780199571666.003.36
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Pathogenesis of HIV infection

Abstract: Over the past three decades of intense research on the contribution of viral and host factors determining the variability in HIV-1 infection outcome, HIV pathogenesis is still a fascinating topic that requires further study. An understanding of the exact mechanism of how these factors influencing HIV pathogenesis is critical to the development of effective strategies to prevent infection. Significant progress has been made in identifying the role of CCR5 (R5) and CXCR4 (X4) HIV strains in disease progression, … Show more

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