Pathogenesis of Plantar Epidermal Cyst: Three-Dimensional Reconstruction Analysis

Choi, Jae Eun; Kwon, In Hyuk; Seo, Soo Hong; Kye, Young Chul; Ahn, Hyo Hyun

doi:10.5021/ad.2016.28.1.133

Cited by 10 publications

(12 citation statements)

References 8 publications

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“…Although epidermal cysts tend to occur in an area with abundant pilosebaceous follicles, such as face, scalp, neck, back and trunk, some rare locations, such as vulvar, have also been reported [6]. When blunt, penetrating injury implant epidermal fragments into the dermis, it may also occur in the hairless skin, such as in soles and palms [7].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Facial Multiple Epidermal Cysts: Successfully Treated by Surgical Excision

Qian

Wang

Shi

et al. 2021

Preprint

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Background Epidermal cysts are common skin tumors that are composed of a keratinocytic cyst wall and central keratin material, which can occur anywhere in the body, especially on the face. However, there are no relevant reports of multiple epidermal cysts coexisting at the same location.Case presentation Here, we report one rare case of facial multiple epidermal cysts, who underwent sequential resection of all cysts. A 45-year-old male presented with facial multiple masses for over 2 years. Physical examination showed multiple cysts with varied sizes on the face. All cysts were smooth, dome-shaped, freely movable, and some of them were attached to the skin by a central pore. The histopathology revealed cysts in the dermis, the wall of which were composed of stratified squamous epithelium, and the cavity were filled with keratin. Therefore, the patient was diagnosed as facial multiple epidermal cysts.Conclusions This is the first well-documented case of multiple epidermal cysts on the face. We report this rare case to highlight that although epidermal cysts usually appear single, they may also appear multiple in the same location, especially in those patients with vigorous sebaceous gland function. Surgical excision is the first-line effective treatment for epidermal cysts.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Facial Multiple Epidermal Cysts: Successfully Treated by Surgical Excision

Qian

Wang

Shi

et al. 2021

Preprint

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“…Although the preferred localisation of epidermoid cysts is hair-bearing skin, they have also been seen on the glabrous skin and mucous membranes. Acquired cysts are thought to develop after blunt, penetrating trauma form either hair follicle infundibulum or eccrine sweat ducts [ 12 ]. The role of human papilloma virus in epidermoid cyst pathogenesis has been debated [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Epidermoid Cysts – A Wide Spectrum of Clinical Presentation and Successful Treatment by Surgery: A Retrospective 10-Year Analysis and Literature Review

Wollina¹,

Langner²,

Tchernev³

et al. 2018

Open Access Maced J Med Sci

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Epidermoid cysts are common benign lesions of hair-bearing, and less often glabrous skin. They can also occur in oral mucosa and internal organs. In case of cutaneous lesions, an epidermal punctum is a clinical diagnostic hallmark. The clinical presentation is variable leading to some differential diagnoses. Diagnosis of epidermoid cysts needs histopathological confirmation – not only of the potential of malignant transformation. The treatment of choice is surgery. We report a retrospective analysis of 2159 epidermoid cysts treated surgically. Most of the cases can be performed under local anaesthesia. The complication rate of 2.2% is low. To avoid relapses, the cyst wall has to be removed completely. Rare genetic disorders with multiple cysts are Gardner and Lowe syndrome.

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“…The epidermal cyst is a benign subepidermal nodule filled with keratin material, and several interchangeable terms are used in the literature - epidermoid cyst, sebaceous cyst, infundibular cyst and epidermal inclusion cysts [4], [5]. This type of cysts predominantly affects the hairy parts of the face, scalp and trunk, and is thought to be the result of cystic ectasia of the infundibular portion of hair follicles [5], [6]. However, it may also occur in the hairless skin (as in soles and palms) as a result of blunt, penetrating injury implanting epidermal fragments into the dermis [6].…”

Section: Discussionmentioning

confidence: 99%

“…This type of cysts predominantly affects the hairy parts of the face, scalp and trunk, and is thought to be the result of cystic ectasia of the infundibular portion of hair follicles [5], [6]. However, it may also occur in the hairless skin (as in soles and palms) as a result of blunt, penetrating injury implanting epidermal fragments into the dermis [6]. Cases in which epidermal cysts have a size greater than 5 cm are referred to as giant epidermal cysts [7].…”

Section: Discussionmentioning

confidence: 99%

Multiple Epidermal Cysts of the Scalp: Dermatosurgical Approach with Favourable Outcome!

Tchernev

Temelkova²,

Yungareva

et al. 2019

Open Access Maced J Med Sci

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BACKGROUND: Epidermal cysts are subcutaneous tissue formations that are most commonly located in the area of scalp, trunk and face. In addition to single ones, the cysts may also be multiple, located near each other. Although they are considered to be a cystic ectasia of the hair infundibulum and mainly affect hairy parts, they can also be seen in the area of palms and feet as a result of trauma. Rare extracutaneous localisations are also described in the medical literature, affecting the oral cavity, intraosseous, cerebrum and sublingual epidermoid cyst. Although the majority of epidermal cysts are benign, a malignant transformation may also occur in the direction of development of squamous cell carcinoma, basal cell carcinoma or Merkel cell carcinoma. Clinically, they are presented as benign lesions, and only histological examination may reveal their malignant potential. Therefore, their surgical removal and subsequent histology are of paramount importance for the elucidation of their origin. CASE PRESENTATION: An 88-year old patient was hospitalized for surgical removal of two tumorous formations in the head area which have been available for many years. During the dermatological examination in the frontal and parietal area of the head, the presence of two oval pink cystic neoplasms, clinically suspected for epidermal cysts, was found. The lesion located in the frontal area was removed by elliptical excision. The resulting surgical defect was closed by undermining the wound edges and mobilisation of the released skin to the middle of the defect, as the latter being closed by single interrupted sutures. In the second surgical session, the lesion located in the parietal region of the head was also removed under local anaesthesia. A so-called island flap was performed in which the tumour formation was removed by oval excision followed by contouring a triangle in the distal direction and transposition of the undermined triangle to the oval surgical defect. The resulting defect was recovered by single interrupted sutures. CONCLUSION: First-line treatment of epidermal cysts is surgical excision, and it is important to remove the cyst wall to minimise the risk of relapses and recurrence. Other treatment options include laser therapy with CO2, erbium-YAG laser or intralesional drainage injection of triamcinolone acetonide.

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Pathogenesis of Plantar Epidermal Cyst: Three-Dimensional Reconstruction Analysis

Cited by 10 publications

References 8 publications

A Rare Case of Facial Multiple Epidermal Cysts: Successfully Treated by Surgical Excision

A Rare Case of Facial Multiple Epidermal Cysts: Successfully Treated by Surgical Excision

Epidermoid Cysts – A Wide Spectrum of Clinical Presentation and Successful Treatment by Surgery: A Retrospective 10-Year Analysis and Literature Review

Multiple Epidermal Cysts of the Scalp: Dermatosurgical Approach with Favourable Outcome!

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