Pathogenic potential of a collagenase gene from<i>Aeromonas veronii</i>

Han, Hyun‐Ja; T, Taki; Kondo, Hidehiro; Hirono, Ikuo; Aoki, Takashi

doi:10.1139/w07-109

Cited by 40 publications

(35 citation statements)

References 37 publications

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“…ECPs, such as collagenase were reported as the important virulent factor to A. veroni bv. veronii (7). In the present study, the ECPs of strain PY50 was lethal to Chinese longsnout catfish and the LD 50 was 11.22 g per fish, and the results were in accordance with the above-mentioned study.…”

Section: Evaluation Of Putative Virulence Factorssupporting

confidence: 92%

Characterization of pathogenic Aeromonas veronii bv. veronii associated with ulcerative syndrome from Chinese longsnout catfish (Leiocassis longirostris Günther)

Cai¹,

Wu²,

Jian³

et al. 2012

Braz. J. Microbiol.

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ABSTRACT273 bacterial strains were isolated from 20 Chinese longsnout catfish samples. The biochemical characteristics of all strains conformed to the species description of Aeromonas veronii bv. veronii on the basis of Vitek GNI+ card. Furthermore, 16S rDNA, gyrB and rpoD sequences of the representative strain PY50 were sequenced and showed high similarity with A. veronii bv. veronii in Genbank. Antibioticresistance of the representative strain PY50 was assessed by the Kirby-Bauer disk diffusion method, and the results showed it was susceptible and moderately susceptible to 13 and 4 of the 21 antimicrobial agents tested. Extracellular products of strain PY50 contained gelatinase, lecithinase, elastase, most of lipase and lipopolysaccharide. Virulence of strain PY50 and extracellular products to Chinese longsnout catfish were also tested, and LD 50 were about 3.47×10 4 CFU per fish and 11.22 g per fish in intraperitoneal injection respectively. This is the first report that A. veronii bv. veronii was the pathogenic agent of ulcerative syndrome in Chinese longsnout catfish.

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Section: Evaluation Of Putative Virulence Factorssupporting

confidence: 92%

Characterization of pathogenic Aeromonas veronii bv. veronii associated with ulcerative syndrome from Chinese longsnout catfish (Leiocassis longirostris Günther)

Cai¹,

Wu²,

Jian³

et al. 2012

Braz. J. Microbiol.

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“…Several factors probably play important roles in this process, in addition to adhesive factors needed for step 1 that are listed under gastroenteritis. Aeromonas species elaborate a wide range of microbial proteases (metalloproteases, serine proteases, and aminopeptidases) capable of degrading complex biologic proteins present in serum and connective tissue, including albumin, fibrinogen, elastin, and collagen (107,132,136,137). Degradation of such tissues and proteins can serve as an energy source for subsequent multiplication.…”

Section: Organotrophic Diseasementioning

confidence: 99%

The GenusAeromonas: Taxonomy, Pathogenicity, and Infection

2010

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SUMMARY Over the past decade, the genus Aeromonas has undergone a number of significant changes of practical importance to clinical microbiologists and scientists alike. In parallel with the molecular revolution in microbiology, several new species have been identified on a phylogenetic basis, and the genome of the type species, A. hydrophila ATCC 7966, has been sequenced. In addition to established disease associations, Aeromonas has been shown to be a significant cause of infections associated with natural disasters (hurricanes, tsunamis, and earthquakes) and has been linked to emerging or new illnesses, including near-drowning events, prostatitis, and hemolytic-uremic syndrome. Despite these achievements, issues still remain regarding the role that Aeromonas plays in bacterial gastroenteritis, the extent to which species identification should be attempted in the clinical laboratory, and laboratory reporting of test results from contaminated body sites containing aeromonads. This article provides an extensive review of these topics, in addition to others, such as taxonomic issues, microbial pathogenicity, and antimicrobial resistance markers.

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“…Protease PrtC from Porphyromonas gingivalis ATCC 53977 (which is no longer available from the ATCC) was the first reported and is also the most studied U32 protease (78). The other members of this family are from Helicobacter pylori, Salmonella enterica serovar Typhimurium, Clostridium beijerinckii, Escherichia coli, and Bacillus subtilis (79)(80)(81)(82). The prtC gene from Porphyromonas gingivalis ATCC 53977 contains 1,002 bp and encodes a 333-residue PrtC protein (78).…”

Section: Bacterial Collagenolytic Proteases From the U32 Familymentioning

confidence: 99%

Diversity, Structures, and Collagen-Degrading Mechanisms of Bacterial Collagenolytic Proteases

Zhang¹,

Ran²,

Li³

et al. 2015

Appl Environ Microbiol

113

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Bacterial collagenolytic proteases are important because of their essential role in global collagen degradation and because of their virulence in some human bacterial infections. Bacterial collagenolytic proteases include some metalloproteases of the M9 family from Clostridium or Vibrio strains, some serine proteases distributed in the S1, S8, and S53 families, and members of the U32 family. In recent years, there has been remarkable progress in discovering new bacterial collagenolytic proteases and in investigating the collagen-degrading mechanisms of bacterial collagenolytic proteases. This review provides comprehensive insight into bacterial collagenolytic proteases, especially focusing on the structures and collagen-degrading mechanisms of representative bacterial collagenolytic proteases in each family. The roles of bacterial collagenolytic proteases in human diseases and global nitrogen cycling, together with the biotechnological and medical applications for these proteases, are also briefly discussed.

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Pathogenic potential of a collagenase gene fromAeromonas veronii

Cited by 40 publications

References 37 publications

Characterization of pathogenic Aeromonas veronii bv. veronii associated with ulcerative syndrome from Chinese longsnout catfish (Leiocassis longirostris Günther)

Characterization of pathogenic Aeromonas veronii bv. veronii associated with ulcerative syndrome from Chinese longsnout catfish (Leiocassis longirostris Günther)

The GenusAeromonas: Taxonomy, Pathogenicity, and Infection

Diversity, Structures, and Collagen-Degrading Mechanisms of Bacterial Collagenolytic Proteases

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