PATHOGENICITY OF AND Β-Lactamase PRODUCTION BY BRANHAMELLA (NEISSERIA) CATARRHALIS

Percival, A.; Corkill, J. E.; Rowlands, Jordan; Sykes, R. B.

doi:10.1016/s0140-6736(77)91562-8

Cited by 87 publications

(35 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The isoelectric point obtained was 5.4, which suggests that this ß-lactamase isolated from N. gonorrhoeae belongs to the TEM-1 type (Van Embden et al 1980). Percival et al (1977) and Phillips (1976) found similar results in other Neisseria strains.…”

Section: Resultssupporting

confidence: 78%

Properties of ß-lactamase from Neisseria gonorrhoeae

Castillo

Sesma

Nader

et al. 1998

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

Section: Resultssupporting

confidence: 78%

Properties of ß-lactamase from Neisseria gonorrhoeae

Castillo

Sesma

Nader

et al. 1998

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

“…This finding remarkably contrasted with the reports of others (6,10,14,(16)(17)(18) that clinically significant isolates of B. catarrhalis often produce ,B-lactamase.…”

contrasting

confidence: 95%

A Case of Acute Catarrhal Conjunctivitis Due to Branhamella catarrhalis

Kawakami

Segawa

Kanai

1983

Microbiology and Immunology

View full text Add to dashboard Cite

Neisseria species and Branhamella catarrha/is are classified in the Family Neisseriaceae (19), along with Moraxella and Acinetobacter. Members of both genera are similar in their morphology and limited metabolic activity, but differ in their genetic similarity. In fact, studies (2) of mole percent guanine and cytosine base composition and deoxyribonucleic acid homology have indicated that B. catarrha/is is obviously distinct from Neisseria species.In recent years, B. catarrha/is has been reported as the causative agent of diverse infectious diseases, e.g, otitis media (3,8,9), maxillary sinusitis (12), purulent bronchitis (12), pneumonia (Il,(13)(14)(15), and empyema (4, II). However, to our knowledge, ophthalmological infections due to this microorganism have rarely been described. We report here a case of conjunctivitis caused by B. catarrha/is in Japan.On May 24, 1982, a previously healthy 58-year-old afebrile Japanese female was admitted to our hospital with a 2-week history of excessive discharge from both eyes, particularly in the evening. Inspection of her eyes disclosed conjunctival congestion without follicular or papillary hypertrophy. She displayed no visual disturbance, i.e., her visual acuity was 1.0, bilaterally. The discharge was taken with sterile cotton swabs for bacteriological examination, and administration of tobramycin eye-drops was started on admission.The specimen was immediately streaked onto four kinds of media, i.e., Heart infusion agar (Eiken, Tokyo) with 5% sheep blood, Chocolate agar containing 7.5% horse blood added to Heart infusion agar (Eiken, Tokyo), modified Drigalski agar (Eiken, Tokyo) and Sabouraud glucose agar (Nissui, Tokyo) with 50 pg/ml of chloramphenicol; the plates were incubated aerobically at 35 C for 20 hr. After incubation, the blood agar and the Chocolate agar plates yielded numerous uniform growth of non-pigmented, opaque, smooth and flattened colonies with a diameter of about I mm. No other colonies could be found on the plates. On both the Drigalski and the Sabouraud glucose agar plates, no visible colonies appeared. Gram's stain of the colonies revealed that they were gram-negative cocci or diplococci which were reminiscent of Neisseria species.Biochemical characterization of the strain was investigated with the Minitek differentiation system (BBL Microbiology Systems, Cockeysville, Md.) using Neisseria 641

show abstract

“…It has been implicated in a wide variety of infectious processes (G. V. Doern, M. J. Miller, R. E. Winn, submitted for publication), including conjunctivitis, otitis media, sinusitis, endocarditis, meningitis, septicemia, and pneumonia, particularly in patients with underlying compromised pulmonary function. Although previously defined as being uniformly susceptible to penicillin (5), several recent studies demonstrated that clinically significant isolates of B. catarrhalis were resistant to penicillin by virtue of their ability to produce /3-lactamase (8,10,(12)(13)(14). Due to the paucity of reported clinical antibiotic trials and in vitro susceptibility studies, little additional information exists regarding the antimicrobial susceptibility of B. catarrhalis.…”

mentioning

confidence: 99%

“…In the second technique, a modification of the Hirt lysis procedure was employed (7). The cells were concentrated 50-to 100-fold by (14). In contra-0.4, and 0.4 jLg/ml, respectively.…”

mentioning

confidence: 99%