Pathogenicity of Pekin duck- and goose-origin parvoviruses in Pekin ducklings

Ning, Kang; Wang, Minghang; Qu, Shenghua; Lv, Junfeng; Yang, Lixin; Zhang, Dabing

doi:10.1016/j.vetmic.2017.08.020

Cited by 26 publications

(26 citation statements)

References 24 publications

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“…Cases of coinfection with parvovirus and circovirus have been reported in pigs, canines, and wild carnivores ( Sun et al., 2015 ; Thaiwong et al., 2016 ; Zaccaria et al., 2016 ; Anderson et al., 2017 ). Novel goose parvovirus–associated virus was identified as the causative agent of BADS ( Chen et al., 2015 , 2016 ), but only 20% clinically susceptible ducks assumed the typical clinical and histologic changes of BADS by being infected with wild NGPV isolate in laboratories ( Ning et al., 2017 ). Our previous study has shown that the positive rate of coinfection of NGPV and DuCV is very high in ducks with BADS ( Li et al., 2018b ).…”

Section: Discussionmentioning

confidence: 99%

“…It can cause high morbidity and high mortality of goslings and young Muscovy ducks ( Brown et al., 1995 ; Jansson et al., 2007 ; Woźniakowski et al., 2009 ). As a GPV-derived virus, NGPV has 89.7 to 96.7% nucleotide homology and similar genome structure with GPV ( Chen et al., 2015 ; Ning et al., 2017 ; Li et al., 2018a ). Its genome includes 2 open reading frames ( ORF ), named the left ORF and the right ORF.…”

Section: Introductionmentioning

confidence: 99%

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Coinfection of novel goose parvovirus–associated virus and duck circovirus in feather sacs of Cherry Valley ducks with feather shedding syndrome

et al. 2020

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Since 2017, an infectious disease, named feather shedding syndrome ( FSS ), has consistently broken out in Cherry Valley ducks in East China. The sick ducks showed the new clinical symptoms of feather shedding and being plucked off with difficulty after slaughter. The high incidence rate of 20 to 70% predominantly happened in ducks of 4 to 5 wk of age, and nearly 40% mortality rate was observed in infected ducks. To explore the possible role of novel goose parvovirus–associated virus ( NGPV ) and duck circovirus ( DuCV ) in this disease, a total of 540 feather sac samples were collected from sick ducks with FSS. The infection rates of NGPV and DuCV in samples were 82.78 and 78.89%, respectively, and the coinfection rate of the 2 viruses was 70.00%. Notably, ducks of 4 to 5 wk of age usually presented obvious and severe FSS in the flocks with high codetection rate of NGPV and DuCV. Furthermore, 9 NGPV strains were isolated from feather sacs and 5 synchronous amino acid mutations were demonstrated in VP3 protein. These results indicated that coinfection of NGPV and DuCV might play an important role in duck FSS disease.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Coinfection of novel goose parvovirus–associated virus and duck circovirus in feather sacs of Cherry Valley ducks with feather shedding syndrome

et al. 2020

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“…NGPV isolated from Cherry Valley ducks and mule ducks was a derivative strain of GPV (Chen et al., ; Li, Lin et al., ; Li, Zhang et al., ). Researchers tried to reproduce the BADS disease in laboratories, but only 20% clinically susceptible ducks assumed the typical clinical and histological changes of BADS by infection in Cherry Valley ducklings with a wild NGPV isolate (Ning et al., ).…”

Section: Introductionmentioning

confidence: 99%

Duck “beak atrophy and dwarfism syndrome” disease complex: Interplay of novel goose parvovirus-related virus and duck circovirus?

J.)

Zhang

et al. 2018

Transbound Emerg Dis

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As a newly emerged infectious disease, duck "beak atrophy and dwarfism syndrome (BADS)" disease has caused huge economic losses to waterfowl industry in China since 2015. Novel goose parvovirus-related virus (NGPV) is believed the main pathogen of BADS disease; however, BADS is rarely reproduced by infecting ducks with NGPV alone. As avian circovirus infection causes clinical symptoms similar to BADS, duck circovirus (DuCV) is suspected the minor pathogen of BADS disease. In this study, an investigation was carried out to determine the coinfection of NGPV and DuCV in duck embryos and in ducks with BADS disease. According to our study, the coinfection of emerging NGPV and DuCV was prevalent in East China (Shandong, Jiangsu and Anhui province) and could be vertical transmitted, indicating their cooperative roles in duck BADS disease.

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“…SBDS was also found in Poland (1995) and Hungary (2009). Since early 2015, SBDS had a sudden outbreak in Cherry Valley duck flocks (Chen et al, ), followed by Pekin ducks (Ning et al, ; Yu et al, ) and mule ducks (Chen et al, ) in various regions of mainland China. After serial experiments, the aetiological agent of SBDS was identified as a variant of GPV (N‐GPV).…”

Section: Introductionmentioning

confidence: 99%

“…The phylogenetic and alignment analysis showed that N‐GPV is a branch of GPV, sharing more than 92.2% nucleotide similarity at the genome level. Although the mortality rate was less than 3.0% in affected flocks, with a morbidity rate of less than 30%, ducks with SBDS showed growth retardation with beak atrophy, which caused large losses in the duck industries (Bian et al, ; Chen et al, , ; Li et al, ; Ning et al, ).…”

Section: Introductionmentioning

confidence: 99%

Novel goose parvovirus in domestic Linwu sheldrakes with short beak and dwarfism syndrome, China

Wan

Liu

Chen

et al. 2019

Transbound Emerg Dis

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Recently, short beak and dwarfism syndrome (SBDS) had a sudden outbreak in Cherry Valley duck flocks, followed by Pekin ducks and mule ducks in various regions of mainland China. This widely spreading infectious disease was characterized by growth retardation, smaller beak and tarsus with high morbidity and low mortality rate. In this study, we identified and characterized virus from domestic Linwu sheldrakes (namely as HuN18) with SBDS. HuN18 isolates shared high nucleotide identity with novel goose parvovirus (N‐GPV). A 5110‐nucleotide full‐length genome sequence of HuN18 was found with no deletion in ITR region. Alignment studies of HuN18 showed 96.8%–99.0% identity with other N‐GPVs and 92.9%–96.3% identity with classic GPV. According to the recombination analysis, HuN18 showed the potential major parent was the N‐GPV sdlc01 strain, the potential minor parent was the classical GPV Y strain, and the secondary potential minor parent was the SYG61v strain. To the best of our knowledge, this is the first report of N‐GPV in domestic Linwu sheldrakes with SBDS; these data provide evidence that attenuated live viruses are involved in genetic recombination with prevailing wild parvoviruses, which contributes to the novel emerging variants of waterfowl parvoviruses.

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Pathogenicity of Pekin duck- and goose-origin parvoviruses in Pekin ducklings

Cited by 26 publications

References 24 publications

Coinfection of novel goose parvovirus–associated virus and duck circovirus in feather sacs of Cherry Valley ducks with feather shedding syndrome

Coinfection of novel goose parvovirus–associated virus and duck circovirus in feather sacs of Cherry Valley ducks with feather shedding syndrome

Duck “beak atrophy and dwarfism syndrome” disease complex: Interplay of novel goose parvovirus-related virus and duck circovirus?

Novel goose parvovirus in domestic Linwu sheldrakes with short beak and dwarfism syndrome, China

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