Pathologic thoracic spine fracture in presence of Parkinson’s disease and diffuse ankylosis: successful management of a challenging condition

Abstract

BackgroundPatients with Parkinson’s disease have higher risk of complications and revision surgery following spine surgery. Spinal fracture in an ankylosed spine is also difficult to treat. We recently treated a case of thoracic spine fracture in a patient with Parkinson’s disease complicating a severely ankylosed spine. There is no report describing surgical treatment of spine fracture in such a difficult condition, thus, we firstly report the case and discuss the reasons for a successful result.Case presentationsA 68-year-old man with Parkinson’s disease had a pathologic thoracic spine fracture at T11. Four days after onset, he was referred to a local hospital because of gradually increasing back pain, but no spinal fracture was pointed out at that time. Because he developed lower extremity bilateral numbness and weakness, he was transported to our hospital, eight days after onset. When referred to our hospital, he exhibited severe back pain and paralysis of the lower extremities due to spinal cord involvement. Emergency surgery was performed. Decompression of T10-11 was performed followed by instrumented spinal fusion from T8 to L2. A dramatic neurological improvement was observed following surgery, and complete bony fusion was achieved. At the final two-year postoperative follow-up, the patient had no pathological symptoms related to spinal fracture and no instrument failure was observed.ConclusionThis patient had Parkinson’s disease and a severely ankylosed spine, both of which may lead to unsatisfactory surgical results from spinal surgery. Generally, patients with Parkinson’s disease have an increased risk for adjacent segment disease and instrument failure. In this patient, fusion surgery did not change the number of fused segments because operated segments were already ankylosed. Because no stress force exists between adjacent vertebral bodies, a severely ankylosed spine may help prevent screw pullout. Thus, treatment of a spinal fracture in an ankylosed spinal segment is a less adverse condition for patients with Parkinson’s disease. Our experience led us to think that a combination of Parkinson’s disease with severely ankylosed spine does not necessarily suggest unsatisfactory outcomes after surgical treatment of spinal fracture.

Consecutive Kummell's Disease Combined with Parkinson's Disease and Experienced Internal Fixation Failure: A Case Report and Literature Review

“…PD is a degenerative neurological disease associated with loss of self‐sufficiency and is characterized by its cardinal features of tremors, rigidity, bradykinesia, and postural instability 16 . Osteoporosis is a “hidden nonmotor face” of PD and a cause of considerable morbidity in the older general population, patients with PD usually have poor bone quality 17,18 . Invernizzi et al 19 .…”

“…16 Osteoporosis is a "hidden nonmotor face" of PD and a cause of considerable morbidity in the older general population, patients with PD usually have poor bone quality. 17,18 Invernizzi et al 19 suggested that osteoporosis is very common in patients with PD, affecting up to 91% of women and 61% of men. Compared with healthy people, the normal activities of PD patients were significantly reduced.…”