Pathological Characteristics, Prognostic Factors and Indications for Limited Surgery in Small Peripheral Adenocarcinoma of the Lung Measuring 2cm or Less in Diameter.

Tajiri, Michihiko; Ishii, Haruhiko; Yamagata, Tatsushi; Ishibashi, Mākoto; Oshita, Fumihiro; Yamada, Katsushi; Nomura, Ikuo; Noda, Kazumasa; Kameda, Youichi; Iida, Mannichi

doi:10.2482/haigan.37.447

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[2][3][4] We previously studied small sized peripheral adenocarcinoma of the lung, and reported that cases with poor central fibrosis and short neoplastic cells in their tumours had a good prognosis, and that there was no recurrence in lepidic growth types sized (10 mm in diameter. 5 6 We performed intentionally limited surgery as part of a prospective trial for BAC with a maximum diameter of (15 mm, and showed that the prognosis was good. 7 Although the ability to detect of minute lung cancer of early BAC is increasing with the increasing prevalence of CT examinations, these discoveries are still rare, and most cases that we treat at our hospital are non-BAC with destroyed alveolar structure.…”

Section: Discussionmentioning

confidence: 99%

Prognosis and morphometrical features of non-bronchioloalveolar cell adenocarcinoma: an assessment of the non-alveolar replacing area and high grade atypical area

Tajiri¹

2006

J Clin Pathol

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Prognosis and morphometrical features of non-bronchioloalveolar cell adenocarcinoma: an assessment of the non-alveolar replacing area and high grade atypical area

Tajiri¹

2006

J Clin Pathol

View full text Add to dashboard Cite

show abstract

Histopathological Features and Tumor Marker Eexpression in Primary Pulmonary Adenocarcinomas

Tamura

Kunimura

1999

The Showa University Journal of Medical Sciences

View full text Add to dashboard Cite

: Forty cases of surgically-resected primary pulmonary adenocarcinoma (PA) were classified according to our proposed microscopic classification (modified Noguchi's opinion) into three subtypes, C, D and F, and the histopathological features and tumor marker expression were compared between each subtype. Overall, type C was the most frequent subtype, and the mean patient age was lower in the type D group, and higher in the type F group. There was a high proportion of females in the type C group. Histopathologically, the malignant potential of PA appeared to be dependent on tumor size, lymph/venous invasion and lymph node metastasis. Type D PA tended to have a higher malignancy than the other types, with type C having the lowest malignancy. The Ki-67 labeling index was highest in type D and lowest in type C. The TUNEL-labeling index was highest in type C cases, and lowest in type D cases. More type D tumor cells were positive for p53 than the other two subtypes. Therefore the histopathological findings of PA correlated well with tumor marker expression, with the more malignant type D cells showing the highest level of expression of the proliferative marker Ki-67 and accumulation of p53. These results support our proposed classification of PA as a practical and useful procedure to determine the grade of malignancy.

show abstract

Pathological Characteristics, Prognostic Factors and Indications for Limited Surgery in Small Peripheral Adenocarcinoma of the Lung Measuring 2cm or Less in Diameter.

Cited by 2 publications

References 0 publications

Prognosis and morphometrical features of non-bronchioloalveolar cell adenocarcinoma: an assessment of the non-alveolar replacing area and high grade atypical area

Prognosis and morphometrical features of non-bronchioloalveolar cell adenocarcinoma: an assessment of the non-alveolar replacing area and high grade atypical area

Histopathological Features and Tumor Marker Eexpression in Primary Pulmonary Adenocarcinomas

Contact Info

Product

Resources

About